Pediatric Dermatology Flashcards
Major differences between children and adult skin:
Kids Skin is:
- Drier
- Chaps easier
- Less hair
- Less collagen
- Weaker epidermal-dermal attachment
- Lose water faster
- Absorbs substances better
When does skin develop?
By 24 weeks gestation
Premature vs mature skin:
- Premature skin 5x thinner
- May seen blood vessels through skin
Protective covering on newborn skin:
- Vernix caseosa
- Protects from excessive dryness in the womb
- Desquamation 24-36 hrs after birth through 3rd week of life
Benign neonatal skin lesions/rashes:
- Erythema Toxicum Neonatorum
- Transient Neonatal Pustular Melanosis
- Miliaria
- Milia
- Cephalic Pustulosis (Neonatal Acne)
Erythema Toxicum Neonatorum:
- Most common rash of full term newborns
- 24 hrs after birth (not at birth)
- Eosinophils in Pustular Fluid
Transient Neonatal Pustular Melanosis:
- Full term infants
- Present at birth
- Higher incidence in babies with dark pigmentation
- Neutrophils in Pustular Fluid
Miliaria (Prickly Heat):
- Newborn rash due to climates too warm for them or over wrapping
- Sweat retention from obstructed eccrine sweat glands in corneum
- Clear pinpoint vesicles (crystallina) or small erythematous papules (rubra)
Milia:
- Small keratin and sebaceous material retention cyst in pilosebaceous follicles
- Face and Nose
- Present at birth
Cephalic Pustulosis (neonatal acne):
- Due to androgens (maternal and endogenous) on sebaceous glands
- Inflammatory papules/pustules without comedones
- Not true acne therefore does not scar
- Forehead nose cheeks
Birthmarks:
- Nevus Simplex
- Nevus Flammeus
- Mongolian Spot
- Cafe-au-lait Spot
Nevus Simplex:
- Pink-red macules that blanch when compressed
- Eyelid, glabella, nape of neck
- Resolve
Nevus Flammeus:
- Port wine stain
- Congenital capillary/venous malformation (dilated vessels)
- Unilateral face
- Associated with Sturge-Weber when located in distribution of CN V ophthalmic branch
- Does not enlarge or involute
Mongolian Spots:
- Dark skin infants
- Blue grey lesion
- Fade but not completely
- Document if unusual site as it may be abuse
- Sacrum and back mostly
Cafe-au-late Spot:
- Hyperpigmented macule
- Found in NF-1 or McCune-Albright syndrome
Diaper Dermatitis:
- Prolonged contact with feces and urine
- Maceration and dampness allows for secondary infection
Irritant/Contact Diaper Dermatitis:
- Contact with chemicals, enzymes in stool, soap etc.
- Convex surfaces of buttock
- Spares Intertriginous creases
Diaper Candidiasis:
- Widespread, raised, beefy red lesion with PINPOINT PUSTULOVESICULAR SATELLITE LESIONS
- Satellite lesions are diagnostic hallmark
- Always look in mouth for thrush
- Can follow systemic antibiotic use
Bacterial Diaper Dermatitis:
- Secondary infection to irritant dermatitis
- Staphylococcal or Streptococcal
- Papules -> Vesicles surrounded by erythema -> golden crust appearance
Seborrheic Diaper Dermatitis:
- Salmon colored greasy plaques with yellowish scale
- Intertriginous areas
- Also check scalp face other areas for seborrheic dermatitis
Seborrheic Dermatitis:
- Plaque with greasy yellow scales
- Sebaceous gland areas
- Scalp hairline
Telogen Effluvium:
- Most common cause of DIFFUSE hair loss
- Occurs within 3 months of stress event
- Mature follicles switch to telogen resting state and shed within 3 months
- Self limiting
Trichotillomania:
- Compulsive urge to pull hair
- Incomplete hair loss
- Anxiety, depression or OCD
Alopecia:
- Due to chronic inflammation
- Normal appearing scalp
- Areata: small patches; most common
- Totalis: entire scalp; autoimmune
- Universalis: all body hair
Traction Alopecia:
- Hairline hair loss
- Due to hairstyles with too much tension
- Non-inflammatory
- Can scar
Tinea Capitis:
- Fungal infection of scalp
- Contagious
- KOH
- Oral antifungals
Aplasia Cutis Congenita:
- Absence of skin on portion of scalp
- May be associated with underlying skull or intracranial malformation
- Hair collar sign: thicker darker hair growth around lesion on scalp that is indicative of CNS abnormality