PDL Flashcards

1
Q

PDL is a ____ CT structure

A

fibrous

*despite being fibrous in nature; it is also has many cells

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2
Q

is the PDL vasculaized and innervated?

A

YES!

-cementum is not

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3
Q

the thin PDL connects?

A

cementum layer to adjacent alveolar bone

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4
Q

where is the thinnest portion of PDL?

A

thinnest portion around middle third of root

*0.15-0.38mm

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5
Q

principle function of PDL?

A
  • supporting teeth in their sockets while permitting them to withstand forces of mastication
  • *sensory receptor for positioning of jaw (full of nociceptors)
  • remodeling for resorbing function
  • nutritive function due to being well-veascularized
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6
Q

principle fibers of the PDL form

A

strong fibrous union between teh root cementum and the bone

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7
Q

ankylosis

A

fusion of root to bone

*PDL fibroblasts may inhibit mineralization so this doesn’t occur

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8
Q

Name and describe the 5 PDL type 1 collagen fibrils bundles called?

A

1) alveolar crest group
- -below CE junction, down, out
2) horizontal group
- -right angle to root surface, apical
3) oblique group
- -oblique angle, coronally towards bone
4) periapical group
- -around apex, base of socket
5) interradicular group
- -in multirooted teeth at crest/furcation

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9
Q

PDL extracellular substances?

A

1) fcollagen fiberes
2) oxytalan fibers
3) glycosaminoglycans and glycoproteins (ground substance)

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10
Q

pressure-tension hypothesis

A

showing tooth displacement leading to compression and tension in the surrounding bone

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11
Q

alveolar bending hypothesis

A

tooth movement causing bending of the alveolar bone

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12
Q

stretched fibre hypothesis**

A

stretching and compression of PDL fibres leading to low and high strain areas in the surrounding bone

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13
Q

name and describe the 5 gingival ligament fibers’s fibers are imbedded

A

1) dento-gingival
- -most numerous, cervical cementum to free/attached gingiva
2) bone of the alveolar crest to free/attached gingiva
3) circular
- -around neck of teeth, free gingiva
4) apically over cementum over the outer cortical plate to alveolar process or vestibule of mouth
5) trans-septal
- -cementum between adjacent teeth, over the alveolar crest

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14
Q

bundle bone

A

where unraveled PDL fibers inter mesh with adjacent fibers and insert into the bone
*contain Sharpey’s fibers

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15
Q

define reversal line

A

location where the last cycle of bone resorption was followed by bone deposition
*the latter resulted from the production by osteoblasts of a thin seam of new bone in which very short Sharpey’s fibers are imbedded

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16
Q

TEM of periodontal ligament fibroblasts are responsible for?

A

1) synthesis of collagen and its assembly into collagen fibers
2) removal of collagen fibers during the continuous remodeling

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17
Q

digestive vacuoles majoridly remove?

A

collagen

*aka intracellular collagen in digestive vacuole

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18
Q

collagen fibrils are digested by _____ enzymes that have been added to the vacuoles

A

lysosomal enzymes

*the presence of these enzymes has been confrimed by cytochemical localization

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19
Q

are neural elements myelinated or not?

A
  • myelinated near the apical end

* unmyetlined more coronally

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20
Q

most of the neural branches near the apical end are?

A

MIXED. consisting of myelinated and non-myelinated axons

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21
Q

the distribution of nerve bracnhes is closely associated with that of?

A

blood vessels

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22
Q

PDL is rich in blood supply originating primarily from? communicating with what vessels?

A
  • *originating off dental arteries that enter through the apical foreman, LOTS of anastomoses
    • ligament vessels also communicate with supraperiosteal vessels
23
Q

the PDL contains an assortment of cells that are capable of generating and maintaining 3 distinct tissues. What are they?

A

1) ligament itself
2) mineralized tissues
3) alveolar bone

24
Q

what are the major cell types of PDL?

A

1) osteoblasts
2) osteoclasts
3) fibroblasts =MOST ABUNDANT
4) epithelial cells= hertwigs
5) macrophages= defense
6) undifferenciated cells
7) cementoblasts
8) vascular elements
() neural elements

25
What is unique about mineralization and Sharpeys fibers?
one end of the fiber may be un-mineralized while the part IN the bond is mineralized--- ONLY the mineralized part is referred to as Sharpey's fiber
26
cementoblasts provide?
ground substance that will imbed the fibers and allow mineralization to proceed
27
formation of mature PDL
* earliest remodeling along tooth and alveolar bone * grow thicker and longer, bone side is wider, until they meet * become organized once they meet
28
fibroblasts are characterized by an ability to achieve an exceptionally high rate of?
turnover of proteins within the extracellular compartment (like collagen)
29
what do integrins do?
bind ECM, serve as mechnotransducers to transmit the stimulus to the cell
30
stimulus for ECM production?
- mechanical stress | - changes in tensile and compressive forces during growth
31
decrease in mechanical stress leads to?
increased collagenase secretion and a thinning of PDL
32
epithelial cells in PDL resemble?
HERS (epithelial cell rests of Malassez) | *
33
importance of undifferentiated mesenchymal cells?
theyare periovascular! differenciate into fibroblasts, osteoblasts, and cementoblasts
34
what are the predominant collagens of PDL
1,3, 12
35
what are the tyeps of elastin fiebrs
1) oxytalan- perpendicular to teeth | 2) eluanin- found within gingival ligament
36
does PDL contain immature or mature elastin protein?
immature forms of oxytalan and eluanin
37
oxytalan fibers
- thought to regualte vascular flow - dense in cervical region of ligament - associated with nueral and vascular elements - perpendicular to teeth OR vertically from cementum surface of root apically
38
1) nerve supplu originates from? | 2) enters from?
1) inferior or superior alveolar nerves 2) apical region and lateral socket walls * *apical region contains more nerve endings
39
interstital space
- present between each bundle of ligament fibers - contains blood vessels and nerves - designed to withstand the impact of masticatory forces
40
ground substance
-amorphous, highly hydrated ~70% water
41
nature of ground substance explains?
why the PDL never mineralizes as it acts as an inhibitor for the process
42
major ground substance components
1) glycosaminoglycan- hyaluronan and dermatan sulfate 2) proteoglycans- proteodermatan sulfate, decorin, biglycan 3) glycoproteins- fibronecin, tenasin and vitrabectib
43
ground substance is critical for withstanding?
- forces - ion water binding/exchange - binding to growth factors - collagen synthesis - fiber orientation
44
PDL gets its blood supply from?
perforating arteries (from the cribiform plate of the bundle bone)
45
is the posterior or anterior supply of blood greater?
posterior
46
ligament in thicker in functioning or non-functioning teeth?
functioning and in areas of greater tension
47
ligament cells are capable or remodeling the ligaement and adjacent?
bone
48
PDL protects the tooth from normal remodeling processes why?
don't want it getting resorbed with typical bone remodeling
49
what is necrosis
cell death
50
when would orthodontic tooth movement no longer be possible?
-when excessiev forces cause necrosis of ligament by cutting off the normal blood supply to the cells
51
can accidentally exfolliated teeth be replatned? complications?
yes | *complication are external root resorption and ankylosis if portion of the ligament are permanently damages
52
what is the mean width of PDL at coronal end of alveolus?
* premolar in heavy function= 0.35mm | * light function= 0.14
53
what is the mean width of PDL in middle of alveolus?
* premolar in heavy function= 0.28 | * light function= 0.10
54
what is the mean width of PDL iat apical end of alveolus?
is somewhere between coronal end and middle