PCSK9 Inhibitor Flashcards
1
Q
Examples
A
Alirocumab
Evolocumab
2
Q
MoA
A
Inhibits PCSK9
= More LDL receptors available to bind circulating LDL
= Lower cholesterol levels
3
Q
Indications
A
Hypercholesterolaemia
Mixed dyslipidaemia
(Alone or with statin)
4
Q
ADR
A
Local injection site reactions
URTI
5
Q
Prescribing Advice
A
X eGFR <30mL/min