PCSK9 Inhibitor Flashcards

1
Q

Examples

A

Alirocumab

Evolocumab

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2
Q

MoA

A

Inhibits PCSK9
= More LDL receptors available to bind circulating LDL
= Lower cholesterol levels

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3
Q

Indications

A

Hypercholesterolaemia
Mixed dyslipidaemia
(Alone or with statin)

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4
Q

ADR

A

Local injection site reactions

URTI

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5
Q

Prescribing Advice

A

X eGFR <30mL/min

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