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Lipid Modifying Drugs > Ezetimibe > Flashcards

Ezetimibe Flashcards

1
Q

MoA

A

Neimann-Pick C1-like (NPC1L1) protein on GI epithelial cells
Antagonist
Inhibits cholesterol absorption from intestine
Increases LDL-cholesterol uptake into cells

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2
Q

Indications

A

Hypercholesterolaemia

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3
Q

ADR

A

Headache, D
Myalgia
Hepatotoxicity

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Lipid Modifying Drugs (5 decks)

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