PCD Flashcards
What Ig is commonly detected in the serum/urine of multiple myeloma patients?
IgG
What are 3 signs reflect changes in the blood of MM patients?
- Stones: Hypercalcaemia
- Fatigue: Anaemia
- Recurrent infection: Neutropenia
What is the diagnostic test for MM?
Serum/Urine electrophoresis
What 2 test would provide a good overview of the disease progression in a patient with MM?
- Skeletal survey
- U&Es
What may be seen on the blood film of an individual with MM?
Rouleaux formation
Which class of drugs can help manage hypercalcaemia and bone pain?
Bisphosphonates
In “fit” patients, with few co-morbitidies, what treatment option gives better outcomes?
High dose chemotherapy followed by autologous stem cell transplants
What are some signs/symptoms of hyperviscosity syndrome?(4)
- Fatigue
- Bleeding
- Visual disturbance
- Cardiac failure
Amyloid deposition is also a feature in which 3 other conditions?
- AD
- T2DM
- Dialysis-related amyloidosis
What stain is used to assess the biopsy of a patient with suspected amyloidosis?
Congo red stain
