Pathways

Question 1

RLE of Glycolysis

Answer 1

Phosphofructokinase (PFK)

Question 2

RLE of Pentose Phosphate Pathway (PPP)

Answer 2

Glucose-6-phosphate Dehydrogenase (G6PD)

Question 3

RLE of Pyruvate Oxidation

Answer 3

Pyruvate Dehydrogenase (PDH)

Question 4

RLE of Kreb’s Cycle

Answer 4

Isocitrate Dehydrogenase (IDH)

Question 5

RLE of Electron Transport Chain (Oxidative Phosphorylation)

Answer 5

Complex IV

Question 6

RLE of Gluconeogenesis

Answer 6

All enzymes reversing glycolysis:
- Pyruvate Carboxylase
- PEP Carboxykinase
- Fructose-1,6-biphosphatase
- Glucose-6-phosphatase

Question 7

RLE of Glycogenesis

Answer 7

Glycogen synthase

Question 8

RLE of Glycogenolysis

Answer 8

Glycogen phosphorylase

Question 9

RLE of Fatty Acid Synthesis

Answer 9

Acetyl-CoA Carboxylase (ACC)

Question 10

RLE of Mevalonate Pathway

Answer 10

HMG-CoA Reductase

Question 11

RLE of Methylerythritol Pathway (MEP)

Answer 11

DOXP Reductoisomerase

Question 12

RLE of Beta Oxidation

Answer 12

Carnitine Palmitoyl Transferase (CPT1)

Question 13

RLE of Ketogenesis

Answer 13

HMG-CoA Synthase

Question 14

RLE of De Novo (nucleotide)

Answer 14

Purine: Amidophosphoribosyltransferase (ATase)
Pyrimidine: Aspartate Transcarbamoylase (ATCase)

Question 15

RLE of Purine breakdown

Answer 15

Xanthine oxidase

Question 16

RLE of Porphyrin synthesis

Answer 16

ALA synthase

Question 17

RLE of Shikimate Pathway

Answer 17

No clear winner

Question 18

Site of Glycolysis

Answer 18

Cytosol

Question 19

Site of Pentose Phosphate Pathway

Answer 19

Cytosol

Question 20

Site of Pyruvate Oxidation

Answer 20

Mitochondrial matrix

Question 21

Site of Kreb’s Cycle

Answer 21

Mitochondrial matrix

Question 22

Site of Electron Transport Chain (Oxidative Phosphorylation)

Answer 22

Inner mitochondrial membrane

Question 23

Site of Gluconeogenesis

Answer 23

Cytosol

Question 24

Site of Glycogenesis

Answer 24

Cytosol

Question 25

Site of Glycogenolysis

Answer 25

Cytosol

Question 26

Site of Fatty Acid synthesis

Answer 26

Cytosol

Question 27

Site of Mevalonic Acid Pathway

Answer 27

Cytosol

Question 28

Site of Methylerythritol Pathway

Answer 28

Plastid

Question 29

Site of Beta Oxidation

Answer 29

Mitochondrial matrix

Question 30

Site of Ketogenesis

Answer 30

Mitochondrial matrix

Question 31

Site of De Novo (nucleotide)

Answer 31

Cytosol

Question 32

Site of Purine breakdown

Answer 32

Cytosol

Question 33

Site of Urea Cycle

Answer 33

Both matrix and cytosol

Question 34

Site of Porphyrin synthesis

Answer 34

Both matrix and cytosol

Question 35

Site of Shikimate Pathway

Answer 35

Cytosol

Question 36

Major human organ of Glycolysis

Answer 36

Universal

Question 37

Major human organ of Pentose Phosphate Pathway

Answer 37

Universal

Question 38

Major human organ of Pyruvate oxidation

Answer 38

Universal

Question 39

Major human organ of Kreb’s Cycle

Answer 39

Universal

Question 40

Major human organ of Electron Transport Chain (Oxidative Phosphorylation)

Answer 40

Universal

Question 41

Major human organ of Gluconeogenesis

Answer 41

Liver

Question 42

Major human organ of Glycogenesis

Answer 42

Liver and Muscle

Question 43

Major human organ of Glycogenolysis

Answer 43

Liver

Question 44

Major human organ of Fatty Acid synthesis

Answer 44

Liver and Adipose

Question 45

Major human organ of Mevalonic Acid Pathway

Answer 45

Liver

Question 46

Major human organ of Methylerythritol Pathway

Answer 46

Other organisms

Question 47

Major human organ of Beta oxidation

Answer 47

Primary: Heart Fasted: Liver, Muscle, Kidney

Question 48

Major human organ of Ketogenesis

Answer 48

Liver

Question 49

Major human organ of De Novo (nucleotide)

Answer 49

Liver

Question 50

Major human organ of Purine breakdown

Answer 50

Liver

Question 51

Major human organ of Urea Cycle

Answer 51

Liver

Question 52

Major human organ of Porphyrin synthesis

Answer 52

Bone marrow

Question 53

Major human organ of Shikimate Pathway

Answer 53

Other organisms