Pathways Flashcards
RLE of Glycolysis
Phosphofructokinase (PFK)
RLE of Pentose Phosphate Pathway (PPP)
Glucose-6-phosphate Dehydrogenase (G6PD)
RLE of Pyruvate Oxidation
Pyruvate Dehydrogenase (PDH)
RLE of Kreb’s Cycle
Isocitrate Dehydrogenase (IDH)
RLE of Electron Transport Chain (Oxidative Phosphorylation)
Complex IV
RLE of Gluconeogenesis
All enzymes reversing glycolysis:
- Pyruvate Carboxylase
- PEP Carboxykinase
- Fructose-1,6-biphosphatase
- Glucose-6-phosphatase
RLE of Glycogenesis
Glycogen synthase
RLE of Glycogenolysis
Glycogen phosphorylase
RLE of Fatty Acid Synthesis
Acetyl-CoA Carboxylase (ACC)
RLE of Mevalonate Pathway
HMG-CoA Reductase
RLE of Methylerythritol Pathway (MEP)
DOXP Reductoisomerase
RLE of Beta Oxidation
Carnitine Palmitoyl Transferase (CPT1)
RLE of Ketogenesis
HMG-CoA Synthase
RLE of De Novo (nucleotide)
Purine: Amidophosphoribosyltransferase (ATase)
Pyrimidine: Aspartate Transcarbamoylase (ATCase)
RLE of Purine breakdown
Xanthine oxidase
RLE of Porphyrin synthesis
ALA synthase
RLE of Shikimate Pathway
No clear winner
Site of Glycolysis
Cytosol
Site of Pentose Phosphate Pathway
Cytosol
Site of Pyruvate Oxidation
Mitochondrial matrix
Site of Kreb’s Cycle
Mitochondrial matrix