Pathways Flashcards

1
Q

RLE of Glycolysis

A

Phosphofructokinase (PFK)

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2
Q

RLE of Pentose Phosphate Pathway (PPP)

A

Glucose-6-phosphate Dehydrogenase (G6PD)

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3
Q

RLE of Pyruvate Oxidation

A

Pyruvate Dehydrogenase (PDH)

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4
Q

RLE of Kreb’s Cycle

A

Isocitrate Dehydrogenase (IDH)

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5
Q

RLE of Electron Transport Chain (Oxidative Phosphorylation)

A

Complex IV

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6
Q

RLE of Gluconeogenesis

A

All enzymes reversing glycolysis:
- Pyruvate Carboxylase
- PEP Carboxykinase
- Fructose-1,6-biphosphatase
- Glucose-6-phosphatase

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7
Q

RLE of Glycogenesis

A

Glycogen synthase

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8
Q

RLE of Glycogenolysis

A

Glycogen phosphorylase

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9
Q

RLE of Fatty Acid Synthesis

A

Acetyl-CoA Carboxylase (ACC)

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10
Q

RLE of Mevalonate Pathway

A

HMG-CoA Reductase

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11
Q

RLE of Methylerythritol Pathway (MEP)

A

DOXP Reductoisomerase

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12
Q

RLE of Beta Oxidation

A

Carnitine Palmitoyl Transferase (CPT1)

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13
Q

RLE of Ketogenesis

A

HMG-CoA Synthase

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14
Q

RLE of De Novo (nucleotide)

A

Purine: Amidophosphoribosyltransferase (ATase)
Pyrimidine: Aspartate Transcarbamoylase (ATCase)

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15
Q

RLE of Purine breakdown

A

Xanthine oxidase

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16
Q

RLE of Porphyrin synthesis

A

ALA synthase

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17
Q

RLE of Shikimate Pathway

A

No clear winner

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18
Q

Site of Glycolysis

A

Cytosol

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19
Q

Site of Pentose Phosphate Pathway

A

Cytosol

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20
Q

Site of Pyruvate Oxidation

A

Mitochondrial matrix

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21
Q

Site of Kreb’s Cycle

A

Mitochondrial matrix

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22
Q

Site of Electron Transport Chain (Oxidative Phosphorylation)

A

Inner mitochondrial membrane

23
Q

Site of Gluconeogenesis

A

Cytosol

24
Q

Site of Glycogenesis

A

Cytosol

25
Q

Site of Glycogenolysis

A

Cytosol

26
Q

Site of Fatty Acid synthesis

A

Cytosol

27
Q

Site of Mevalonic Acid Pathway

A

Cytosol

28
Q

Site of Methylerythritol Pathway

A

Plastid

29
Q

Site of Beta Oxidation

A

Mitochondrial matrix

30
Q

Site of Ketogenesis

A

Mitochondrial matrix

31
Q

Site of De Novo (nucleotide)

A

Cytosol

32
Q

Site of Purine breakdown

A

Cytosol

33
Q

Site of Urea Cycle

A

Both matrix and cytosol

34
Q

Site of Porphyrin synthesis

A

Both matrix and cytosol

35
Q

Site of Shikimate Pathway

A

Cytosol

36
Q

Major human organ of Glycolysis

A

Universal

37
Q

Major human organ of Pentose Phosphate Pathway

A

Universal

38
Q

Major human organ of Pyruvate oxidation

A

Universal

39
Q

Major human organ of Kreb’s Cycle

A

Universal

40
Q

Major human organ of Electron Transport Chain (Oxidative Phosphorylation)

A

Universal

41
Q

Major human organ of Gluconeogenesis

A

Liver

42
Q

Major human organ of Glycogenesis

A

Liver and Muscle

43
Q

Major human organ of Glycogenolysis

A

Liver

44
Q

Major human organ of Fatty Acid synthesis

A

Liver and Adipose

45
Q

Major human organ of Mevalonic Acid Pathway

A

Liver

46
Q

Major human organ of Methylerythritol Pathway

A

Other organisms

47
Q

Major human organ of Beta oxidation

A

Primary: Heart
Fasted: Liver, Muscle, Kidney

48
Q

Major human organ of Ketogenesis

A

Liver

49
Q

Major human organ of De Novo (nucleotide)

A

Liver

50
Q

Major human organ of Purine breakdown

A

Liver

51
Q

Major human organ of Urea Cycle

A

Liver

52
Q

Major human organ of Porphyrin synthesis

A

Bone marrow

53
Q

Major human organ of Shikimate Pathway

A

Other organisms