Pathophysiology of Thrombosis & Embolism Flashcards
What are the three part of Virchow’s triad ?
1: changes in the blood vessel wall
2: changes in the blood constituents
3: changes in the pattern of blood flow
What does Virchow’s triad describe ?
A change to normal laminar blood flow
Explain the relationship between Atheroma and thrombosis
The parthenogenesis of thrombosis begins with an Atheromatous plaque
What are the lines of Zhan ?
A layered mesh-work of platelet deposits and fibrin which eventually form a thrombosis.
List the factors that cause thrombosis ?
1: Stasis
2: Hypercholesterolemia
3: Any disruption to normal laminar flow
3: Virchow’s triad
What is an embolism ?
A dislodged piece of thrombosis
List the factors causing embolism ?
1: Previous DVT
2: Cardiac failure
3: Trauma
4: Post-op
5: Post-partum
6: Oral contraceptive