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Systems: The Cardiovascular System > Drainage & the Lymphatic System > Flashcards

Drainage & the Lymphatic System Flashcards

1
Q

What are the three types of capillary ?

A

Continuous
Fenestrated
Discontinuous

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2
Q

What type of capillary is found in the blood brain barrier?

A

Continuous

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3
Q

What two mechanisms does clotting involve ?

A

1: Formation of the platelet plug
2: Formation of fibrin clot

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4
Q

What turns fibrinogen into fibrin ?

A

Thrombin

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5
Q

What does thrombin do to fibrinogen

A

Turns it into fibrin

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6
Q

What does the endothelium produce that inhibits platelet aggregation ?

A

Prostacylcins and NO

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7
Q

What do prostacyclins and NO do and where are they produced in ?

A

They inhibit platelet aggregation within the endothelium

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8
Q

What inhibits thrombin production and is produced by the endothelium ?

A

Tissue Factor Pathway Inhibitor (TFPI)

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9
Q

What does TFPI do ?

A

Inhibits thrombin production

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10
Q

What can bind to thrombin and deactivate it ?

A

Thrombomodulin

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11
Q

What does thrombomodulin do ?

A

Binds to thrombin and deactivates it

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12
Q

What does heparin do to thrombin ?

A

Deactivates it

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13
Q

What else can the endothelium secrete that will help to digests the clot ?

A

Tissue Plasminogen activator (t-PA)

This creates plasmin which digests the clot

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14
Q

Define bulk flow

A

Flow through the capillaries and the forces that act on them bringing water in and taking water out

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15
Q

What is bulk flow driven by ?

A

Hydrostatic pressure and osmotic pressure

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16
Q

What is filtration ?

A

When water moves from an area of high concentration in the capillaries to low concentration in the tissues

17
Q

What is re-absorption ?

A

When water moves from an area of high concentration in the tissues to a low concentration in the capillaries

18
Q

What is starlings law ?

A

The filtration and absorption of fluid between the capillary beds an the tissues depends top the balance between hydrostatic pressure and osmotic pressure

19
Q

What is oedema ?

A

The accumulation of excess fluid in the interstitium

20
Q

What are four causes of oedema ?

A

Lymphatic obstruction
Raised CVP
Hyperproteinaemia
Increased capillary permeability

Systems: The Cardiovascular System (15 decks)

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