Pathophysiology Of Strokd Flashcards
How is stroke defined?
Rapidly developing symptoms
Clinical signs of disturbance in cerebral function
Symptoms lasting 24h+ or leading to death
No apparent cause other than vascular
What area does the vertebrobasilar circulation supply?
Thalamus
Cerebellum
Brainstem
Occipital lobe
What area does the lenticulostriate artery supply?
Basal ganglia (lentiform nucleus/striatum)
What area does the middle cerebral artery supply?
Lateral aspects of the cortex (temporal lobe and lateral frontal lobe)
What area does the anterior cerebral artery supply?
Medial aspect of the frontal and parietal cortex
Corpus callosum
Cingulate gyrus
What area does the posterior cerebral artery supply?
Occipital lobe
Inferior temporal lobe
What are the main causes of ischaemic stroke?
Atherosclerosis
Penetrating artery disease (lacunae)
Cardiogenjc embolism
Cryogenic stroke
Other rare causes
What are the causes of cardiogenic embolism?
Atrial fibrillation
Valve disease
Ventricular thrombosis
How would a lacunae stroke present?
Pure motor stoke, pure sensory stroke, ataxic hemiparesis or dysarthria (indicating small vessel)
No lesion on imaging or a deep infarct
What kind of stroke does atherosclerosis usually result in?
Embolic stroke
What factors make a plate unstable?
Ulceration
Lipid content
Haemorrhage
Inflammation
Embolisation
What is carotid stenosis?
Blocking of the carotid artery by plaque causing narrowing
What is the 2 year risk of stroke in people with severe stenosis?
1 in 4
What chronic form of cerebrovascular disease
At arise from carotid stenosis?
Cerebral hypoperfusion
Where are aneurisms most likely to happen?
At junctions where vessels are weaker
Particularly at circle of Willis
