Pathophysiology Flashcards
What are auto-rhythmic cells?
Generate action potentials spontaneously
1% of myocardial cells
Do not contribute to contractile force
ANS innervates the heart
What is the conducting pathway of the Heart?
1) SA node (pacemaker)
2) AV node
3) AV bundle ( bundle of HIS
4) Right and left bundle branches
5) Purkinje fibers
Electrical Pathway of the SA node
1) SA depolarizes
2) Moves rapidly to the AV node via inter nodal pathway
3) Depolarization spreads more slowly across atria (so atria can finish filling) Conduction is slow though AV node
Electrical Events of the Cardiac Cycle
P wave
P wave: Atrial depolarization
PR segments
time between end of atrial depolarization and onset of ventricular depolarization
Conducting through the AV nose and continuing atrial contraction
Q wave
R wave
S wave
Down the apex
Up from the apex
Up the ventricle
ST segment
time between end of ventricular depolarization and onset of ventricular repolarizaton
Continuing ventricular contraction
PR Interval (combination of waves and segments)
time between onset of atrial depolarization and ventricular depolarization
AV blocks
QT interval
Time between onset of ventricular depolarization and end of repolarization
long QT syndrome (abnormality of ion channel on the cardiac cells)
What is a normal HR
60-100 bpm
average 70 bpm
What is tachycardia?
fast resting heart rate
greater than 100 bpm
What is bradycardia?
Slow resting heart rate
less than 60 bpm
Some endurance athletes have bradycardia but is a physiological advantage
What is Primary AV Block?
increase duration of PR interval
increase delay between contraction
What is secondary AV block?
Slowed conduction through AV node
lose 1 to 1 P wave and QRS complex
lose 1 to 1 atrial to ventricular contraction
What is tertiary AV block?
loss of conduction through AV node
P wave is independent of QRS
Atrial and ventricular and contractions are independent