Pathology1 Flashcards
The congenital absence of many, but not all, teeth is known as: • hypodontia • oligodontia • diphyodontia • anodontia
oligodontia (usually six or more)
refers to the absence of only a few teeth?
Hypodontia
type II of dentinogenesis imperfecta features?
most common, only the dentin abnormality exists with no bone involvement
Which type of dentinogenesis imperfecta features multiple pulp exposures, periapical radiolucencies, and a variable radiographic appearance?
• type I
• type II
• type III
type III (In Type III, the dentin appears thin, and the pulp chambers and root canal are extremely large)
type I of dentinogenesis imperfecta features?
occurs in patients that have osteogenesis imperfecta
dentinogenesis imperfecta appearance?
The teeth exhibit an unusual translucent or opalescent appearance with color variation from yellow-brown to gray
Hypercementosis is the excessive deposition of secondary cementum on the roots. Any tooth may be involved, however, which teeth are most frequently involved? • molars • incisors • premolars • canines
premolars (Hypercementosis produces no significant clinical signs or symptoms and a continuous and unbroken periodontal membrane space)
Hypercementosis is found in which disease?
Paget disease
An enamel defect resulting from the incomplete formation of the enamel matrix is called: • enamel pearls • enamel hypocalcification • enamel hypoplasia • regional odontodysplasia
enamel hypoplasia
If only one permanent tooth is affected with enamel hypoplasia, it is usually caused by physical damage or periapical infections to the primary tooth that this permanent tooth replaced. This is known as ?
“Turner hypoplasia.”
? involves the hard tissues that are derived from both epithelial (enamel) and mesenchymal (dentin and cementum) components
Regional odontodysplasia
Regional odontodysplasia features?
short roots, open apical foramina, and enlarged pulp chambers. The thinness and poor mineralization quality of the enamel and dentin layers have given rise to the term “ghost teeth.”
the complete division of a single tooth bud. The divided teeth are seen as completely separate with no connection to each other except each tends to be mirror image of the other?
Twinning
Clinically, percussion of the ankylosed tooth produces a ?
dull sound
Which of the following statements concerning amelogenesis imperfecta are true? Select all that apply.
• it is an inherited condition that is transmitted as a dominant trait
• because of the enamel malformation, the teeth of individuals with amelogenesis imperfecta are often discolored, sensitive to temperature changes, and painful to brush
• it only affects the permanent teeth
• it causes the enamel to be soft and thin
• the teeth appear yellow because the dentin is visible through the thin enamel
• the teeth are easily damaged and susceptible to decay
- it is an inherited condition that is transmitted as a dominant trait
- because of the enamel malformation, the teeth of individuals with amelogenesis imperfecta are often discolored, sensitive to temperature changes, and painful to brush
- it causes the enamel to be soft and thin
- the teeth appear yellow because the dentin is visible through the thin enamel
- the teeth are easily damaged and susceptible to decay
which malocclusion is a common clinical finding in amelogenesis imperfecta?
Open bite
The abnormal loss of tooth structure due to nonmasticatory physical friction is referred to as: • erosion • abfraction • attrition • abrasion
abrasion
Abfraction lesions ?
are cervical erosive lesions that cannot be attributed to any particular cause; causing the enamel to “pop” off starting at the base of the tooth and exposing the gumline of the tooth to excessive wear.
Which of the following can cause intrinsic staining of teeth? Select all that apply. • dentinogenesis imperfecta • erythroblastosis fetalis • porphyria • fluorosis • diabetes mellitus • pulpal injury • internal resorption • tetracyclines
- dentinogenesis imperfecta
- erythroblastosis fetalis
- porphyria
- fluorosis
- pulpal injury
- internal resorption
- tetracyclines
the expectation of an endodontic therapy success rate in internal resorption?
relatively high success rate
the expectation of a endodontic therapy success rate in external resorption?
of no assistance, since the source of the lesion is not in the pulp
A patient with which type of amelogenesis imperfecta will have teeth with demonstrate enamel that varies from thin and smooth to normal thickness with grooves, furrows, and/or pits?
• type I (hypoplastic)
• type II (hypomaturation)
• type III (hypocalcified)
type I (hypoplastic)
Dentin dysplasia is a rare condition that has been subdivided into ?
- type I or radicular type
* a more rare type II or coronal type
In Type I dentin dysplasia, roots appear extremely short, and pulps are: • normal • somewhat smaller • extremely large • completely obliterated
completely obliterated
Type I dentin dysplasia clinical features?
- Type I dentin dysplasia
- teeth are generally mobile, frequently abscess, and can be lost prematurely
- teeth show greater resistance to caries
- extremely short roots
- obliterated pulp chambers
- periapical radiolucencies
Type II dentin dysplasia (coronal dysplasia) features?
- Coronal pulps of permanent teeth are usually enlarged
* Absence of periapical radiolucencies
Leukemia is a group of bone marrow diseases involving an uncontrolled increase in: • red blood cells (erythrocytes) • platelets • plasma cells • white blood cells (leukocytes)
white blood cells (leukocytes)
four types of leukemia ?
- Acute lymphocytic leukemia (ALL): most common type in children
- Acute myelogenous leukemia (AML): most malignant type
- Chronic lymphocytic leukemia (CLL): least malignant type
- Chronic myelogenous leukemia (CML): 2 distinct phases, invariably fatal
A 48-year-old female patient walks into your office. She states that she is diagnosed with some disease which she can't remember the name of. Her physician wants her to follow up with you, her dentist, regularly to watch out for cancer of the tongue and throat. She also has a bald tongue, and states that her fingernails "look funny." What disease does she have? • aplastic anemia • plummer-vinson syndrome • pernicious anemia • cushing syndrome
plummer-vinson syndrome (iron-deficiency anemia is common in it)
Aplastic anemia ?
a form of anemia in which the capacity of the bone marrow to generate red blood cells is defective
Aplastic anemia types?
I. Primary: unknown cause, affects young adults. It is usually fatal.
2. Secondary: caused by exposure to toxic agents, such as radiation, chemicals, or drugs (for example, chloramphenicol). It can occur at any age. Prognosis is good
the most serious and life-threatening blood dyscrasia associated with drug toxicity ?
Aplastic anemia
What disorder is a result of a genetic mutation causing the substitution of glutamic acid by a valine and results in dental radiographs with enlarged marrow spaces? • cystic fibrosis • muscular dystrophy • polio • sickle cell anemia
sickle cell anemia (abnormal hemoglobin, the lamina dura and the teeth are unaffected)
in sickle cell anemia the life span of red blood cells is reduced ?
from 120 to 20 days.
The category of pigmented (usually purple) lesions in the skin caused by extravasation of blood from the capillaries is known as: • petechiae • purpura • ecchymosis • varicose veins
purpura (Tooth extractions are contraindicated due to the tendency for excessive bleeding)
Which of the following is true of acute leukemias? Select all that apply.
• slow onset and progession
• characterized by the appearance of immature, abnormal cells in the bone marrow and peripheral blood and frequently in the liver, spleen, lymph nodes, and other parenchymatous organs
• marked by the effects of anemia, which are usually severe (fatigue, malaise), an absence of functioning granulocytes (prone to infection and inflammation), and thrombocytopenia (hemorrhagic diathesis)
• moderate enlargement of the spleen, liver, and lymph nodes. Fever and very high ESR
• leukocyte counts vary greatly from patient to patient
• characterized by the appearance of immature, abnormal cells in the bone marrow and peripheral blood and frequently in the liver, spleen, lymph nodes, and other parenchymatous organs
• marked by the effects of anemia, which are usually severe (fatigue, malaise), an absence of functioning granulocytes (prone to infection and inflammation), and thrombocytopenia (hemorrhagic diathesis)
• moderate enlargement of the spleen, liver, and lymph nodes. Fever and very high ESR
• leukocyte counts vary greatly from patient to patient
(Acute leukemias have a rapid onset and progression)
You have a dental patient who mentions during his health history that he has an "overactive thyroid".You ask him about his medications and he states that he doesn't know what he takes now, but at one time he took methimazole. He had to stop that because it "really tore up my gums and the roof of my mouth." Which condition of the blood is most commonly caused as a reaction to medication that could have caused these symptoms? • thrombocytopenic purpura • agranulocytosis • sickle cell anemia • peutz-jeghers syndrome
agranulocytosis (The most characteristic feature of this condition is the presence of infection, particularly in the oral cavity)
One important aspect agranulocytosis ?. Histologically, this is pathognomonic of agranulocytosis.
there is little or no apparent inflammatory cell infiltration around the lesions
difference between agranulocytosis and cyclic neutropenia?
Cyclic neutropenia is an unusual form of agranulocytosis with severe gingivitis. The severe ulcerations seen in agranulocytosis usually do not occur
The term used to describe a leukemia in which leukemic cells appear in the blood but there is no significant increase in the number of white blood cells is called:
• aleukemic leukemia
• subleukemic leukemia
• stem cell leukemia
subleukemic leukemia