Pathology Terms

Question 1

Hyperkeratosis?

Answer 1

Increased thickness of the keratin layer

Question 2

Parakeratosis?

Answer 2

Persistence of nuclei in the keratin layer -> usually seen in psoriasis or pre-malignant conditions (epidermis is proliferating too quickly)

Question 3

Acanthosis?

Answer 3

Increased thickness of epithelium

Question 4

Papillomatosis?

Answer 4

Irregular epithelial thickening

Question 5

Spongiosis?

Answer 5

Intercellular oedema in the epidermis
Oedema between squames appears to increase prominence of intercellular prickles
If severe, vesicles filled by oedema fluid develop

Question 6

Rete ridges?

Answer 6

Downward thickening of the epidermis between the dermal papillae

Question 7

Acantholysis?

Answer 7

Lysis of intercellular adhesion sites

Question 8

What are the 4 main classification of inflammatory skin disease?

Answer 8

Spongiotic - intraepidermal oedema
Psoriasiform - Elongation of rate ridges
Lichenoid - basal layer damage
Vesiculobullous - blistering

Question 9

What condition is characterised by spongiotic - intraepidermal oedema?

Answer 9

Eczema

Question 10

What is psoriasiform?

Answer 10

Elongation of rate ridges