Pathology of Periapical Periodontitis Flashcards

1
Q

What is periapical periodontitis?

A

Inflammation of periodontal ligament and other tissues around tooth apex.

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2
Q

What are the causes of periapical periodontitis?

A

Usually due to spread of infection following death of the pulp

Extrusion of antiseptics through apex during root canal treatment

A high filling or biting suddenly on a hard object sometimes causes an acute, usually transient, periapical periodontitis

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3
Q

What tends to be the clinical findings associated with acute periapical periodontitis?

A

History of pulpitis

Escape of exudate into periodontal ligament causes a small amount of tooth extrusion

Pain well localised: Tender to touch/percussion

Tooth not vital & not responsive to vitality tests unless pulpal necrosis limited to single canal in multirooted tooth

As inflammation becomes more severe, there can be intense throbbing pain

Infection usually remains localised

Abscess can develop

Can spread in tissue planes causing facial swelling Rarely local lymphadenopathy

Very rarely, osteomyelitis or cellulitis

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4
Q

How would you manage acute periapical periodontitis?

A

Endodontic treatment

Extraction

Open drainage through skin or mouth if needed due to abscess causing swelling

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5
Q

What can you see radiologically & pathologically relating to acute periapical periodontitis?

A

Radiology: bone resorption not had time to happen so only radiographic change may be widening of periodontal ligament space

Pathology: acute inflammation i.e presence of neutrophils

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6
Q

What is the pathology of chronic periapical periodontitis like?

A

-Chronic inflammation and granulation tissue

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7
Q

What are the clinical signs relating to chronic periapical periodontitis?

A
  • Low grade infection
  • May follow acute periapical periodontitis
  • Tooth is not vital, unless very rarely pulpal necrosis is limited to a single canal in a multi-rooted tooth.
  • Symptoms may be minimal

-Can be tender to percussion

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8
Q

What are the radiological signs of chronic periapical periodontitis?

A

-Often diagnosed on identification of a periapical radiolucency

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9
Q

What are the sequelae of chronic periapical periodontitis?

A

Periapical granuloma and in some cases, subsequently radicular cyst

Acute exacerbation with suppuration/abscess, cellulitis and sinus formation

Very rarely, focal sclerosing osteitis

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10
Q

How do you treat chronic periapical periodontitis?

A

Extraction or root canal treatment

A radicular cyst may need to be enucleated (removal)

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11
Q

What are some features of periapical granulomas and how does it affect the tooth?

A

Most asymptomatic

May be history of pulpitis

But can have coexisting pulpitis and therefore be symptomatic

Tooth is not vital and will not be responsive to vitality tests unless the pulpal necrosis is limited to a single canal in a multirooted tooth

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12
Q

What are some radiographic features of periapical granulomas?

A

-75% of apical inflammatory lesions

-Most discovered on routine radiographs

-Tooth shows loss of apical lamina dura

-Bone resorption appearing as a radiolucency that may be circumscribed or ill-defined.

Size variable:
-Small barely perceptible to 2 cm
-Larger lesions may represent radicular cysts
-Can’t definitely distinguish from a radicular cyst on size alone

Root resorption can be seen rarely

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13
Q

What is important to remember about a periapical granuloma?

A

A periapical granuloma is NOT granulomatous inflammation so don’t get them confused!

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14
Q

What is the relation of periapical granulomas to apical scars?

A

It’s a defect created by periapical inflammatory lesions, may rarely heal by filling with dense fibrous tissue rather than normal bone

These fibrous periapical scars occur most frequently when both the facial and lingual cortical plates have been lost

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15
Q

What would you pathologically see regarding a periapical granuloma?

A

See chronically inflamed granulation tissue at apex of a nonvital tooth

Defensive reaction secondary to the presence of bacteria in the root canal with spread of related toxins into the apical zone

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16
Q

What is the relation of periapical granulomas to apical abscesses?

A

Periapical granulomas may arise after quiescence of a periapical abscess or may develop as the initial periapical pathology.

17
Q

What is a cyst?

A

An epithelial-lined cavity

18
Q

What is focal sclerosing osteitis?

A

Very rare condition which is most frequent in children & young adults but can occur in older people

It’s localised, usually uniform bone sclerosis (radiodense) adjacent to tooth apex of a tooth with periapical periodontitis

And most occur in lower premolar and molar areas

19
Q

What is the relation of periapical granulomas to radicular cysts?

A

Cell rests of Malassez (epithelial remnants from tooth development) lying in vicinity of periapical area may show reactive proliferation to inflammation / infection leading a radicular cyst.

20
Q

What can focal sclerosing osteitis resemble?

A

Several other intrabony lesions

21
Q

How does focal sclerosing osteitis usually progress?

A

85% of cases of focal sclerosing osteitis will regress, either partially or totally, after root canal treatment or tooth extraction

A residual area of condensing osteitis that remains after resolution of the inflammatory focus is termed a bone scar