Pathology of Dz Flashcards
Study of cause and development of structural and functional changes in body caused by dz
Pathology
Abnormality of structure or function with recognizable clinical signs
Disease
Disease factors..
How bad is the dz?
Host factors…
How capable is the host? Can host fight off the dz?
5 developing factors of disease
- Exposure-immunity or infection
- Infection- clinical dz, immunity or incubation
- immunity- short term or long term
- incubation- immunity, sub clinical carrier or clinical dz
- clinical dz- recovery, chronic dz or death
7 Pathological tissue changes and examples:
- Size- mm or cm lxWxh
- Number- TNTC
- Shape- or irregular
- Color
- Consistency/Integrity- thick or thin; firm or solid
- Edema/ Fluid accumulation
- Location/Distribution/Odor
All diseases have an __________ cause
underlying
Vitamin D approach:
- Vascular
- Iatrogenic/Idiopathic
- Toxic/Traumatic
- Anomaly(congenital)
- Metabolic
- Immune-mediated/Infectious
- Neoplastic/Nutritional
- Degenerative/Developmental
Diseases and infections naturally transmitted between man and other vertebrate animals
Zoonosis
Staff Education for prevention:
Reportable dz’s, Vac/parasite program, not allow clients to restrain pets, avoid scratches/bites, vac for rabies, wear gloves/wash hands
Deworming recommendation for kittens/puppies
every 2 wks until 8wks of age
then monthly until 6 months of age
Fecal exams are ______ times a year
1-4
Heart worm test dogs _________, cats __________
annually; periodically
Viewing death
Necropsy
Purpose of necropsy:
determine cause of death confirm diagnosis study pathology to find prevention or treatment prevent zoonosis ease minds legal reasons
Equipment needed for necropsy:
PPE
zoonosis awareness
instruments/tools
DO NOT FREEZE
Positing small animals for necopsy:
left lateral then dorsal
Positioning for ruminants and horses for necropsy:
left lateral
Positioning birds for necropsy:
dorsal
Positioning fetus for necropsy:
right lateral
*Examine fetal membranes, weight, measure crown to the rump
Procedure for necropsy:
- External exam
- Abdominal cavity (GI tract tie off) (Liver, pancreas, spleen, kidney, bladder, repro. organs)
- Thoracic cavity (Remove tongue, thymus, thyroid, esophagus, trachea, lungs, heart)
- Head (start ventral)
- Muskuloskeletal system
Preserving histopathology samples
Fixatives
Formalin is _____ % neutral buffered formaldehyde
10
Not more than ____cm in thickness
1.0
Formalin:Tissue volume?
10:1
Large samples include _____ ____________ ______ and _____% formalin
brain, spinal cord, bone
50
Additional testings:
- Bacterial cultures-collect fluid and tissue
- Cytology
- Virus isolation
- Stomach contents
- Individual or herd cases
- External parasites placed in alcohol
- LABEL and SHIP SECURELY
- Radiographs