Pathology Flashcards
What is the auditory meatus lined by?
- epidermis
What lines the middle ear?
- columnar mucosa
What are the 3 bones that make up the ossicles of the middle ear?
- malleus
- incus
- stapes
What is contained within the inner ear?
- cochlea and vestibular apparatus
What lines the nasal vestibule?
- squamous epithelium
What lines the nose, sinuses and nasopharynx?
- pseudostratified ciliated columnar epithelium
What are the 3 major salivary glands?
- parotid
- submandibular
- sublingual
Serous cells of the salivary glands stain what colour?
- dark staining
Mucinous component of the salivary glands stain what colour?
- clear grey staining
Define otitis media?
- inflammation of the middle ear
What usually causes otitis media?
- infection spread through eustachian tube
Cholesteatoma appears as what?
- pearly white mass in middle ear
- locally destructive
Acquired cholesteatoma may be a result of what?
- chronic otitis media
- perforated tympanic membrane
What is the most common malignant tumour of the ear?
- squamous cell carcinoma
Vestibular schwannoma is associated with what nevrve?
- vestibular portion of vestibulocohlear nerve
- CN VIII
Symptoms of vestibular schwannoma?
- tinnitus
- ear ache
- loss of balance
What should you aim to rule out in a bilateral vestibular schwannoma in the young?
- NF type 2
Nasal polyps in a young patient, what should you rule out/
- Cystic fibrosis
Granulomatosis with polyangitis is also known as/
- Wegner’s granulomatosis
Granulomatosis with polyangitis is what?
- a small vessel vasculitis
- cANCA associated
3 types of sinonasal papilloma
- inverted
- exophytic
- oncocytic
Causes of sinonasal papilloma?
- HPV
- organic solvents
Symptoms of sinonasal papilloma?
- blocked nose
Potential causes of nasopharyngeal carcinoma?
- epstein barr virus
Causes of a contact ulcer?
- benign response to injury
- GORD
- Intubation
Squamous cell papilloma may be related to?
- HPV types 6 and 11
Paraganglioma is a tumour arising from what?
- neuroendocrine cells
Paraganglioma may secrete?
- catecholamines
Paraganglioma may be linked to what endocrine condition?
- MEN 2
E6 of HPV blocks what pathway?
- p53
E7 of HPV blocks what?
- RB
- tumour suppressor
Sialolithiasis means?
- stones in the salivary glands
Tumours in the salivary glands are most common on what gland?
- parotid
Warthin’s tumour has a strong association with what?
- smoking
- tumour of parotid