Pathology

Question 1

Pineal tumours can sometimes secrete what hormone?

Answer 1

HCG

Question 2

Parinaud’s syndrome in pineal tumours is caused by what effect?

Answer 2

Compression of the dorsal midbrain

Parinaud’s syndrome:
1- Loss of pupillary reaction
2- Vertical gaze paralysis
3. Loss of optokinetic nystagmus
4. Ataxia

Question 3

What type of cerebral tumour is similiar to a testicular seminoma?

Answer 3

Pineal tumours

Question 4

What cerebral tumour stains positive for GFAP (Glial fibrillary acidic protein) and is associated with microcyts and Rosenthal fibres (eosinophilic corkscrew)

Answer 4

Astrocytomas

Question 5

What cerebral tumour stains positive for synaptophysin and is characteristed by Homer-Wright rosettes (small blue cells surrounding central neutrophil)?

Answer 5

Medulloblastoma

Question 6

What cerebral tumour is of ependymal cell origin and is charateristed by perivascular pseudorosettes and rod-shaped blepharoplasts near the nucleus?

Answer 6

Ependymoma

Question 7

What cerebral tumour is derived from the remnants of Rathke pouch and is characteristed by cholesterol crystals within the tumour.

Answer 7

Cranipharyngioma