Pathology Flashcards
Germ cell deficiency is the most common cause associated with what condition?
testicular hypoplasia
What is an easy way to eliminate testicular hypoplasia?
selection for testicular size
Which species (3) is cryptorchidism most common in
horse, pig, and dog
why is a cryptorchid testis ineffective at spermatogenesis?
temperature is higher in abdomen than in the scrotum
What does cryptorchidism predispose to in dogs?
sertoli cell tumors
___________ is the presence of only one testis. the other is congenitally absent. this is only common in alpacas.
monorchidism
what is the general rule for reversal in testicular degeneration?
mild and short duration – reversable, ok prognosis
chronic and severe – permanent, poor prognosis
hormonal imbalance (secondary to pituitary neoplasia and/or steroid-producing tumors of the adrenal or testis) is a factor that can lead to what condition?
testicular degeneration resulting in decreased production of spermatocytes
T/F: androgen levels cannot reach levels high enough systemically to support spermatogenesis
true
Describe the gross nature of a degenerate testis.
firm, pale parenchyma, +/- fibrous streaks, and bulges less/not at all when cut.
T/F: all causes of testicular degeneration appear similar at the morphologic level
true
What are the major causes of orchitis (testicular inflammation) in the following species:
dog
horses
Dog – brucella, distemper
Horse – brucella, aberrant migration of Strongylus edentatus
what is the prognosis for orchitis in most cases?
poor – d/t the delicate anatomy of tubules.
Stasis of sperm in tubules will result in chalky white small foci. These can progress to small granulomas and are common finding in degenerate testes. Do these impair fertility?
no
_____________ results in infarction of the testis. It occurs most commonly in the horse and dog. This condition is very painful, acute, and obvious.
torsion of spermatic cord
Describe leydig cell tumors and which species they are most common in.
round, soft, pale/orange/orange-brown
dog, horse
describe sertoli cell tumors and which species they are most common in.
lobulated, white, and firm
all species, cryptorchid dogs*
they secrete hormones that feminize the host (estrogen)
___________ is a rare tumor occuring most commonly in dogs, horses, and rams. They are soft, gray, and round. These are usually not malignant.
seminoma
__________ is a neoplasm of young animals consisting of all 3 germ cell layers. They are usually benign and occur most commonly in horses
terratoma
lymphosarcoma are most common in what species?
rams
_________________ will result in blind efferent ductules and stasis of sperm. Rupture will subsequently occur, resulting in a sperm granuloma. This incites an autoimmune response.
failure of efferent ductules to connect to the epididymal duct