Pathogens (Unit 3) - Flashcards
Commonly called a germ
Pathogen
What Is a Pathogen?
A disease-causing organism
What Is a Disease?
A change in the normal way a body
functions that causes harm to the
body
______ are the changes in
our bodies that occur when we
get a disease
Symptoms
Example of symptoms:
sneezing, runny nose - symptoms of a cold
Diseases are classified into 2
groups based on their causes:
if they can be spread from person
to person or not
A disease that can spread from person to
person. Also called infectious disease or
contagious disease
Communicable Diseases
_________ always caused by exposure to pathogens, leading to pathogens entering, reproducing in and infecting your body
communicable disease
Example of communicable disease
rubella
for communicable disease Most pathogens are:
bacteria, viruses, fungi, or protists
ARE ALL EXAMPLES OF?
COVID-19
Rabies
HIV
Tuberculosis
Measles
Chickenpox
Communicable Diseases
People may be born with the disease
Non-Communicable Diseases
refers to the way the body of an organism works
Physiology
Any disease that can not be spread
from one person to another
Non-Communicable Diseases
example of non-communicable disease:
sickle-cell anemia
is the structure of organisms
Anatomy
the origination and development of a disease
Pathogenesis
Or disease may develop as the person
ages example:
(example: heart disease)
Bacteria:
Most belong to the Kingdom _______
Eubacteria.
the study of the spread, control, and prevention of
disease in a group of persons
Epidemiology:
A few bacteria belong to Kingdom ________. These are usually found in _________ (e.g. gut of animals, swamps, salt lakes,
hot springs)
Archaebacteria
extreme environments
Bacteria are Are extremely _____; range in size from 0.2 -1 µm
Some stick together in small groups called _______
small
colonies
Endospores can be killed by exposing them to pressurized steam at 121 degrees Celsius for 10-15 minutes in a process called ______ in a machine called an _______
sterilization
autoclave
Bacteria can be classified by shape:
Bacillus (plural: bacilli) -
rod-shaped
bacteria Reproduce asexually by _______
binary fission
All Bacteria Share Certain Characteristics -
_______-celled
_______ - DNA not surrounded by a nuclear membrane
No membranes around cell organelles
DNA is made up of a ____ chromosome
Single-celled
Prokaryotic - DNA not surrounded by a nuclear membrane
No membranes around cell organelles
DNA is made up of a single chromosome
Coccus (plural: cocci) -
spherical-shaped
Spirillum (plural: spirilla) -
spiral-shaped
An endospore is a thick wall surrounding the _______ and a small amount of cytoplasm (the rest of the cell is degraded, releasing the endospore)
genetic material
Endospores can survive:
boiling water, drying out or other extreme conditions
Some bacteria form a protective structure called an ______ when exposed to harsh conditions
endospore
Cells will emerge from endospores and begin normal growth when:
conditions are favourable
The term ‘_____’ refers to bacteria than form chains.
strep
_______ reproduction occurs by the process of binary fission
Asexual
The term ‘_____’ refers to bacteria that cluster together like grapes.
staph
Two common bacterial infections are _____ infections and _____ infections.
staph and strep
- Why do doctors often do a throat swab before prescribing a medication?
-need to know what your infected with (can’t give whatever)
- Should we kill off all bacteria?
-no, some help (good bacteria)
-in digestive system
- Why are scientists more concerned with bacteria that can form endospores?
-can last a long period of time without showing symptoms and randomly pop up during favourable conditions
staph/strep questions
Bacteria can also reproduce sexually by _______
conjugation
Reproduction in Protists -
Unicellular organisms with distinct ______
Can reproduce asexually - _______, _______
Can reproduce sexually - _______,______
nuclei
binary fission, budding
conjugation, fusion of gametes
Binary Fission:
________ is copied then identical genetic material ends up in each new cell
The DNA (chromosome)
In Binary Fission The cell then makes a ______ to divide the cell into two
cross wall
in Conjugation Two cells connect to form a _____
sex pilus
Conjugation -
The transfer of _______ from one bacterium to another by direct contact - not common among bacteria
genetic material
A small lifeless particle that carries out no metabolic functions on its own
Viruses
Cannot reproduce on its own
Viruses
In Conjugation The donor cell transfers _____ to the recipient cell - altering their genetic characteristics
plasmids
Reproduction in Fungi -
_______,_______ organisms that live as saprobes or parasites (includes mushrooms, yeasts, and molds)
Eukaryotic, heterotrophic
Fungi have ______ but lack chlorophyll
rigid cell walls
Characteristics of Viruses - (4)
Virus - Latin for poison
Carry out no life function on their own
Cannot be seen with a light microscope
Measured in nanometres(nm)
Fungi Can reproduce sexually - ______, _______
conjugation, fusion of gametes or spores
Fungi Can reproduce asexually - ______, _______, _______
binary fission, budding, fragmentation
Viruses: Living or Non-Living?
LIVING - (3)
-Made of DNA/RNA and a protein
-Possesses genetic material that is capable of mutation
-Can adapt to changing environment
Basic Structure of Viruses - (4)
Range in size from 20 nm to 400 nm
Inner nucleic acid core - could be DNA or RNA
Outer protein coat called a capsid
Varies greatly in appearance/shape
Viruses: Living or Non-Living?
NON-LIVING - (4)
-Have no cellular organelles
-Unable to produce their own energy or proteins
-Must rely on host cells for cellular functions and reproduction
-Are assembled; cannot grow
Has a unique tadpole shape with a distinct head and tail region
Bacteriophages
A category of viruses known as “eaters of bacteria”
Bacteriophages
Examples (2)
Rabies virus -
Can infect many mammals including rodents, dogs, racoons, bats, and humans
Human cold virus-
Infects cells of the upper respiratory tract
Viral Diversity -
Viruses are selective - specific viruses will only enter specific cells. These specific cells are the host range
This limits the number of host species, tissues, or cells that a virus can infect
Viral Replication -
Viruses _______ - not reproduce!
replicate
Process by which the virus and its genetic material are duplicated 2 ways:
Lytic cycle
Lysogenic cycle
Lytic Cycle -
Can take as little as _____minutes and produce hundreds of new virus particles
25 to 45
Four steps in lytic cycle
Attachment
Synthesis
Assembly
Release
The four steps explained of the lytic cycle
1) Attachment - Virus attaches to host cell and injects genetic material
2) Synthesis - Viral DNA/RNA ‘hijacks’ the host cell to produce viral parts
3) Assembly - The viral parts are assembled to form new viruses
4) Release - Host cell lyses (breaks open) and newly formed viruses are released
Lysogenic Cycle -
Virus _____ its genetic material into a host cell
injects
When host cell replicates, the______ also replicates
viral DNA
_____ combines with the host cell’s DNA
Viral DNA
A ______ activates the viral DNA and the lytic cycle begins
trigger
Triggers example
temperature, stress, chemicals, shock
The pathogen is a protist called plasmodium carried by mosquitoes.
Malaria
1) Would you consider pathogens with lysogenic cycles more serious/dangerous?
-yes
-can be dormant with host cell for many years so you don’t see symptoms before a trigger causes is to be harmful
-persist silently within host/remain hidden/hard to find and control
3) With respect to changing temperatures and climates, how can this affect the spread of disease?
-Warmer diseases can expand disease-carrying things such as mostquotes, ticks or fleas
-Changes in precipitation can cause waterborne disease
-Can be a trigger/perfect condition for some disease
2) What can we do to help prevent malaria?
-Mosquito control
-Personal protection (repellent, long sleeve, sleep under net)
A set of specific practices performed under controlled conditions with the goal of minimizing contamination by pathogens.
Aseptic Techniques
Aseptic Practices in the Workplace:
-handwashing
-sterile or disposable equipment
-Proper disposal
-use different droppers
-Wear gloves/ masks
Food Safety
Be aware of what you eat, and be careful how you prepare it.
Ensure what needs to be refrigerated is refrigerated
Be sure temperature controls in refrigerators and freezers are working properly
Wash counters, cutting boards, and utensils frequently with soap and hot water,
especially after preparing poultry and other meats
Wash fresh fruits and vegetables before eating
Cook ground beef until you can no longer see any pink (ground beef cannot be
eaten raw)
Medication:
Use antibiotics exactly as prescribed.
Take them for the full course prescribed by your doctor, but not for
colds or other non-bacterial illnesses; never share your antibiotics
Report to your doctor any quickly worsening infection or any
infection that does not get better after you take a prescribed
antibiotic.
Keep immunizations up to date. Follow recommended
immunizations. And don’t forget your pets.
Travel:
Stay alert to disease threats when you travel to
other parts of the world.
Get all recommended immunizations, and use
protective medications for travel, especially to
areas with malaria.
Don’t drink untreated water while hiking or
camping.
If you become ill when you return home, tell your
doctor where you’ve been.
Wildlife:
Be cautious around all wild and domestic animals that are not
familiar to you.
After any animal bite, clean the skin with soap and water, and seek
medical care immediately
Important Steps to Avoid Ticks:
Wear light colored clothing, including long sleeve
shirts and pants when outside. Light colored
clothing will make ticks more easily seen on
clothing before they have a chance to attach to the
skin.
Tuck pants into socks and shirts into pants to
cover skin as much as possible.
- How can cuts to the housekeeping budget in hospitals affect the spread of disease?
-decreased cleanliness and sanitation standards
-not proper disinfection of surface, equipment and rooms
-spread more disease causing pathogens such as bacteria/virus
-not enough staff for cleaning
- What can you do to stop the spread of disease when visiting a nursing home?
-wash hands often for 20 secs
-use hand sanitizer
-avoid coming if not well
-wear mask
-maintain distance
- In Ontario, all business serving food must pass an inspection by Canadian Food Inspection Agency. Would you eat at an establishment that got a ‘Yellow warning’ rating? Why or why not?
-no, may pose possible risk of infection
-hygiene concerns
-risk of cross contamination