Patho of SI and LI

Question 1

contains phagocytic cells, lymphocytes, plasma cells that synthesize Ig
─ protection vs bacteria

Answer 1

Lamina propia

Question 2

secrete ions and water
─ deliver IgA to the lumen
─ site for cell division and renewal

Answer 2

Crypts

Question 3

secrete mucus that protects surface epithelium and provides ideal condition for nutrient uptake

Answer 3

goblet

Question 4

columnar absorptive cells with microvilli (finger-like projections)

Answer 4

villi

Question 5

absence of ganglion cells can lead to Hirschprung disease

Answer 5

Intrinsic Nerve Control (Myenteric Plexus)

Question 6

four phases of nutrient absorption

Answer 6

Intraluminal
terminal
transepthelial transport
Lymphatic transport

Question 7

inborn error of metabolism, an inability to synthesize Apolipoprotein B so there will be a defect in the synthesis and transport of lipoprotein

Answer 7

Abetalipoproteinemia

Question 8

accumulation of histiocytes

Answer 8

Whipple disease

Question 9

Histologic findings of chron’s

Answer 9

transmural inflammation, non-caseating granuloma, dilated and sclerosed lymphatics, lymphoid aggregates in wall

Question 10

Characterized by isotonic stools which persists even with fasting.

Answer 10

SECRETORY DIARRHEA

Question 11

Due to excessive osmotic forces exerted by unabsorbed luminal solutes

Answer 11

OSMOTIC DIARRHEA

Question 12

Transmural infarction, caused by:

Answer 12

Thrombosis, emboli of superior mesenteric artery

Venous thrombosis

Question 13

due to non-occlusive

hypoperfusion, infections, digitalis and norepinephrine

Answer 13

Mucosal and mural infarction

Question 14

usually arise from endocrine cells, secreteamines or aminopeptide (APUD formation)

Answer 14

carcinoid

Question 15

Factors that lead to carcinoid syndrome:

Answer 15

Presence of hepatic metastases

─ Production of sufficient amounts of secretory products

Question 16

Adenoma - more common in

Answer 16

SI

Question 17

rare cause of chronic intestinal obstruction due to
congenital absence of ganglion cells in the
parasympathetic Auerbach & Meissner complexes of
the rectum

Answer 17

MEGACOLON

Congenital (Hirschsprung’s disease)