Patho Exam 2 spring 2015 - everything Flashcards
meningitis is
Inflammation of the meningitis (Layers over the CNS)
Causes of meningitis
Infection- viral, bacterial, fungus (other bugs- worms)
inflammation of the meningitis- scarring
~There is CSF in the area, so it if there is too much scaring, may have a block of the CSF~Hypercyphale~ s/s: Headache, confusion, vomiting, loss of cons, loss of function
Encephalomyelitis
~Inflammation of brain and spinal cord~Everything is inflamed~Flexion will cause an extreme about of pain (SLR too)~Pt will usually be put in a coma ~This is all very similar to the other two, but all put together
what happens to athletes twho get a concussion?
Concussion testing battery baseline
retest before they can return to play after concussion
Free of symptoms counts as day 1 (still might not be exactly where they were before)
At what ranchos levels would you probably want to use the Glasgow-Coma scale too?
Definately levels I and II
possibly level III
Details on NP
masters level degree
Responsibilities are a lot like a Physicians Assistant
must be a Registered Nurse prior to becoming a NP
Eschemic Cascade process (5)
- •Excess neurotransmitter substances
- •Limits energy production
- •Influx of calcium ions with neuronal membrane pump failure
- •Free radical formation
- •Inflammatory factors
Medical Management of stroke (Treatment)
considerations besides pharma or surgery (10)
Doctor will assess and treat the following
- •Blood flow
- •Blood pressure
- •Cardiac output
- •Fluid/electrolyte balance
- •Blood glucose
- •Seizures (seizures not too common)
- infections
- •ICP - pressure monitor
- we need to know how low to stay and monitori it. Highest is 20
- •Bladder and Bowel
- constipation and incontinance etc
- •Skin
what are some risk factors for stroke?
(three main ideas)
Risks (similar to Heart Disease)
- minorities
- age 65 or older
what is the severity of the stroke/CVA dependant upon? (4)
- –Location of ischemia
- –Size
- –Structures injured
- –Availability of collateral circulation
What is the difference between a craniotomy and craniectomy?
What is the difference between a craniotomy and craniectomy?
Both procedures involve removing a portion of the skull, usually to perform surgery on the brain. The difference is that after a craniotomy the bone is replaced and after a craniectomy the bone is not replaced immediately.
http://www.phoenixchildrens.org/medical-specialties/barrow-neurological-institute/programs-services/neurotrauma/faqs-neurosurgery
Vetebrobasilar Artery Srroke potentially involves which three structures
- Vertebral Artery
- Basialr ARtery
- Circle of Willis
- supplies blood to the Posterior Cerebral ARtery if possible
Homonymous hemianopsia definition
Homonymous hemianopsia, or homonymous hemianopia, is hemianopic visual field loss on the same side of both eyes.
what can a Vertebrobasilar ARtery Stoke in the Vertebral artery effect?
cerebelum
medulla
Hemorrhagic stroke: typical attributes of pt (risk factors) (3)
- pts tend to be younger
- HTN
- anatomical malformations
- arteriovenous malformations
- can cause lack of blood flow??
- arteriovenous malformations
how long does it take to reach maximum cerebral edema?
Max accumulation in 3-4 days
What forms the extracranial blood supply? (2 pairs)
Internal carotid arteries
Vertebral arteries
why might a craniotomy or craniectomy be performed?
to relieive pressure in the cranium and make room for swelling
What are some different areas of stroke? (4)
Different areas of stroke
- Anterior Cerebral Artery
- Posterior Cerebral Artery
- Middle Cerebral Artery
- Homunculus
Medical Management of stroke (Treatment)
Three Pharmacology options
•Pharmacology options
- –Anticoagulant
- –Antiplatelet
- –Antihypertensives
is the carotid artery easy or hard to fix?
easier to fix
the vessels in the brain are much harder
coma
a coma is a state that lacks both awareness and wakefulness.
is a state of unconsciousness lasting more than six hours in which a person: cannot be awakened; fails to respond normally to painful stimuli, light, or sound; lacks a normal sleep-wake cycle; and, does not initiate voluntary actions.[1] A person in a state of coma is described as being comatose.
http://en.wikipedia.org/wiki/Coma
what are two types of pts that the FIM can be used for for prognosis and as an evaluation meausre?
Stroke patienst
TBI patients
what is anterograde amnesia?
antrograde (can’t learn new things)
Details about CNA
Helps pt go to batheroom, etc.
Could be your best freind
Is overseen by RN or LPN
Do not need a degree (must go to an intensive course)
what is the etiology of stroke? (6-ish)
Similar to Cardiac
- Atherosclerotic narrowing of arteries
- Ischemic issues, clot growing or staying stationary
- Thromboembolic formation
- breaking free and flowing downstream
- blocking anything distal to where clot is
- Ischemia etc.
what is considered normal ICP (for shappy)?
•Normal ICP 4 to 15 mmHg
Myasthenia gravis
~grave muscle disease~takes on average 2 years to diagnosis ~autoimmune- don’t know the cause~problem at the NM junction
Ischemic Cascade happens in what time frame?
3-4 hours
What can be used to assess cognitive state?
glascow coma scale
why is it good to look at any images we can get our hands on in the hospital?
The more we see these images along with symptoms, the more we understand them and we can develop expertise
What is CIP also called?
SIRS- systematic inflammatory response syndrome
Viral meningitis
~If it’s just alcohol, it will not make a superbug; ~you have to get to the doc within 24 hours to stop the virus; if you get there after, it will just suppress~Let it runs its course in healthy inds~Pools are great places to get meningitis (more on the viral- they like the warm)
what is a craniotomy?
Craniotomy = removal of scull
What is a cranioplasty?
Cranioplasty is a surgical repair of a defect or deformity of a skull.
what does IADLs stand for?
Instrumental Activities of Daily Living
Is a stroke preventable?
yes the same old lifestyle stuff
What could be a risk from cervical manipulations?
a hemorrhagic stroke
but it is not well documented because it doesn’t happen immediately
what is a brain hematoma?
A bleed on the brain
what does DAI stand for?
Diffuse Axonal Injury
what is left negelct?
a neuropsychological condition in which, after damage to one hemisphere of the brain is sustained, a deficit in attention to and awareness of one side of space is observed.
http://en.wikipedia.org/wiki/Hemispatial_neglect
what is CIDP?
~Different form GBS because GBS is acute; this is the recurrent form of GBS ~Will have a more spontaneous healing process than GBS~Will treat all these type of pts the same
what is declarative memory?
Declarative memory: the ability to recall facts and previous events. Language based. can tell you facts and information. (I think they could tell you a procedure even if they can’t do it: like I might be able to tell you the steps of how to do a back handspring, but I cannot do one)
_______
Declarative memory consists of facts and events that can be consciously recalled or “declared.” Also known as explicit memory, it is based on the concept that this type of memory consists of information that can be explicitly stored and retrieved.
Declarative memory differs from procedural memory, which encompasses skills such as the use of objects or movements of the body that are deeply embedded and are performed without being aware.
http://www.livescience.com/43153-declarative-memory.html
explain testing for Lacunar Syndrome
There are different diagnostic techniques for Lacunar Syndrome diagnosis
Sometimes it fails and we can’t find it but we treat the symptoms anyway
if outpoutches are found in the brain do they ever prophylactically clip them?
yes
MOI for SCI
(three motions, four results)
some sort of method of acceleration/deceleration where the brain tissue smashes into the cranium
- Accerleration
- Deceleration
- Rotation
If any of these causes:
- Shearing,
- tearing,
- compression, or
- displacement of brain tissue
some method of trauma
Head doesn’t actually have to hit something, but brain must slosh agains something
brain can rotate into scull
What are two types of strokes?
which is most common and by how much?
- Thromboembolic strokes: 80% of strokes (most common)
- Hemorrhagic (pts call it an aneurism): 20% of strokes
how many pts with strokes oare found in Inpatient Rehab Units (IRUs)?
Stroke pts are the largest percent of people admitted into IRUs
What is a lacunar stroke?
Dr. Shappy said: “A stroke caused by clots in the more distal vessels”
So I think she meant the penetrating arteries, but also closer to the surface
Wikipedia says:
Lacunar stroke or lacunar infarct (LACI) is a type of stroke that results from occlusion of one of the penetrating arteries that provides blood to the brain’s deep structures. Patients who present with symptoms of a lacunar stroke, but who have not yet had diagnostic imaging performed, may be described as suffering from lacunar stroke syndrome (LACS).
http://en.wikipedia.org/wiki/Lacunar_stroke
Vetebrobasilar Artery Srroke potentially involves which three structures
- Vertebral Artery
- Basialr ARtery
- Circle of Willis
- supplies blood to the Posterior Cerebral ARtery if possible
Hemorrhagic stroke: typical attributes of pt (risk factors) (3)
- pts tend to be younger
- HTN
- anatomical malformations
- arteriovenous malformations
- can cause lack of blood flow??
- arteriovenous malformations
Locked in Syndrome
Damage to Basilar Artery (Vertebrobasilar Artery STroke)
- •Bilateral ventral Pons damage
- •Tetraplegia
- •CN V-XII involved
- •Vertical eye movements and blinking remain
- •Consciousness and sensation intact only
do we work with pts with myasthenia gravis?
~We will not work with this pt~We can have this type of pt referred and we would referred them to the doc
what happens after ischemic cascade?
Cerebral Edema
What type of stroke is FAST made for?
Middle Cerebral Artery Syndrome
(specifically on the left - speech)
Ischemic Cascade happens in what time frame?
3-4 hours
Levels of Consciousness Again (all the way to alert)
- Alert
- Lethargic (bringman: pt may fall asleep during eval)
- Obtunded (bringman: pt may fall asleep during transfers): Seep often. Delayed reaction or reduced interests
- Stupor: Brief time of arousal
- Minimally Consicous: barely not in vegetative state. localized response. may respond to something held out to them.
- Vegetatie state: eyes open but cannot follow commands (may have wake/sleep cycle)
- Persistant Vegetative State (3 months?)
- Coma: state that lacks both awareness and wakefullness
myasthenia gravis- NM junction
~ACh crosses~Our body will make antibodies against his one site- Will block the ACh receptor site~This is not a strength issue- we cant make them better~They are weak bc there is no ACh to make the muscle fire ~Cholinesterase inhibitor: Mestinon; Helps to increase the amount of ACh in the cleft~If you remove the thymus, it can somehow help
Encephalitis- uncal herniation
~Brain stem comes through the foreman magnum~Probably won’t recover; this will kill you
Sequelae of TBI: Inderect impairments
•Indirect impairments
- –Other systems effected by same trauma, etc. or as a result of condition
I think Heterotrophic ossification was given as an example
How would the decision be made about prophylactically clipping anurisms?
weigh the risks and benefits
how distal is the aneurism?
how hard is it to reach?
what does the pt want to do?
is the carotid artery easy or hard to fix?
easier to fix
the vessels in the brain are much harder
Homonymous hemianopsia definition
Homonymous hemianopsia, or homonymous hemianopia, is hemianopic visual field loss on the same side of both eyes.
A stroke effecting what side of the body will clue you in to probable speech problems?
A stroke that effects the right side of the body
(because Broca’s and Wernickie’s areas are on the left side of the brain)
what is a Carotid Endarterectomy?
rotor-rooter procedure for corotid artery
What is a lacunar stroke?
Dr. Shappy said: “A stroke caused by clots in the more distal vessels”
So I think she meant the penetrating arteries, but also closer to the surface
Wikipedia says:
Lacunar stroke or lacunar infarct (LACI) is a type of stroke that results from occlusion of one of the penetrating arteries that provides blood to the brain’s deep structures. Patients who present with symptoms of a lacunar stroke, but who have not yet had diagnostic imaging performed, may be described as suffering from lacunar stroke syndrome (LACS).
http://en.wikipedia.org/wiki/Lacunar_stroke
Fungal meningitis
~Where to get it- a dirty env~Not easy to get~A steroid has become tainted with the fungus- BAD (500 got it, 40 died)
how does encephalitis start?
~Usually will not start with encephalitis~Usually have an infection in a different part of the body
describe/draw the circle of willis
Encephalitis- do you have to be in the hospital?
YES~If we get to them soon enough, we may need to drain some CSF~CSF tap~reduce Intracranial pressure (ICP)~normal values range from 1-15/20~Can do a bolt: It is a short term VCP shunt; Used in very bad cases; Need to be at level of the head
What are three things that can be used to manage a high ICP?
- Intraventricular catheter
- Subural screw
- Epidural sensor
which is worse: bacterial or viral meningitis?
Bacterial is worse than viral
what kinds of deficits do strokes cause?
(name two that we shouldn’t forget about)
All kinds of stuff (she had us come up with several, but I couldn’t write fast enough)
Don’t forget autonomic functions
Proprioception
TBI: Most common age group injured
young males
A stroke effecting what side of the body will clue you in to probable speech problems?
A stroke that effects the right side of the body
(because Broca’s and Wernickie’s areas are on the left side of the brain)
Locked in Syndrome
Damage to Basilar Artery (Vertebrobasilar Artery STroke)
- •Bilateral ventral Pons damage
- •Tetraplegia
- •CN V-XII involved
- •Vertical eye movements and blinking remain
- •Consciousness and sensation intact only
are you likely to see Lacunar Syndrome patients in rehab?
not unless they have had lots of them
my be more likely to see in outpatient
(because their impairments are usually not as severe)
Medical Management of stroke (Treatment)
surgery options (2)
•Surgery options
- –Endarterectomy
- –Hemorrhagic
s/s of meningitis
~Headache~Fever~Malaise ~Fatigue~Nausea (that means that the pressure is really high~Neck flexion can replicate the symptoms
Where do PTs come in during medical management of SCI?
After the emergency is managed and pateint is stable
We do our own neuro eval, check ICP, etc.
Medical Management of stroke (Treatment)
Three Pharmacology options
•Pharmacology options
- –Anticoagulant
- –Antiplatelet
- –Antihypertensives
Medical Managment of TBI: Patient Stable(3)
- –Neurologic evaluation
- –Surgical evacuation
- –ICP
Six cognitive states
- Coma
- Vegetative State
- Persistant Vegettative state
- Minimally Conscious
- Stupor
- Obtunded Phase
myelitis
inflammation of the spinal cord
what is a focal injury?
–Area of impact
–Can result in bruising (hematoma), swelling (edema), Slicing/laceration/tearing of brain, coup-contra coup effect.
From Wikipedia:
Focal and diffuse brain injury are ways to classify brain injury: focal injury occurs in a specific location, while diffuse injury occurs over a more widespread area. It is common for both focal and diffuse damage to occur as the result of the same event; many traumatic brain injuries have aspects of both focal and diffuse injury.[1] Focal injuries are commonly associated with an injury in which the head strikes or is struck by an object; diffuse injuries are more often found in acceleration/deceleration injuries, in which the head does not necessarily contact anything, but brain tissue is damaged because tissue types with varying densities accelerate at different rates.[2]
http://en.wikipedia.org/wiki/Focal_and_diffuse_brain_injury
How would the decision be made about prophylactically clipping anurisms?
weigh the risks and benefits
how distal is the aneurism?
how hard is it to reach?
what does the pt want to do?
Where do strokes fall in leading causes of death in the USA? (are they common or not?)
what is a demographic who is at greater risk?
Strokes are Third leading cause of death in the United States (not a test number)
- strokes are in abundance
- millions of people who have had a stroke at some level
- minorities are at greater risks (2x higher)
- probably because of preventative care
what is Heterotrophic ossification?
Heterotopic ossification (HO) is the process by which bone tissue forms outside of the skeleton.
http://en.wikipedia.org/wiki/Heterotopic_ossification
describe FIM & FAM scale
- Complete Independence (timely, safely)
6 Modified Independence (extra time, devices)
5 Supervision (cuing, coaxing, prompting)
4 Minimal Assist (performs 75% or more of task)
3 Moderate Assist (performs 50%-74% of task)
2 Maximal Assist (performs 25%-49% of task)
1 Total Assist (performs less than 25% of task)
What could be a risk from cervical manipulations?
a hemorrhagic stroke
but it is not well documented because it doesn’t happen immediately
Middle Cerebral Artery Syndrome (7)
- •Frontal, Parietal and Temporal Lobes
- •Second main branch off internal carotid
- •Lateral aspect of cerebral hemisphere and subcortical
- •Contralateral symptoms
- •Sensory and motor
- –Face, UE greater than LE
- •Left hemisphere
- –Broca’s area- speech production, expressive aphasia
- –Wernicke’s area- speech comprehension, receptive aphasia
- •Right hemisphere
- left neglect
what percentage of stroke pts will end up in a nursing home in the first year?
25% stroke pts will end up in nursing home
- if you have a stroke and you are older, not as many people want to take you home, or they may not be able to take you home
- number is probably a lot higher after a year
explain testing for Lacunar Syndrome
There are different diagnostic techniques for Lacunar Syndrome diagnosis
Sometimes it fails and we can’t find it but we treat the symptoms anyway
what are IADLs?
(It stands for Instrumental Activities of Daily Living)
More advanced ADLs
Example: writing checks or grocery shopping (more than just basic self-care in the home. They require more complex reasoning)
what percentage of stroke pts will end up in a nursing home in the first year?
25% stroke pts will end up in nursing home
- if you have a stroke and you are older, not as many people want to take you home, or they may not be able to take you home
- number is probably a lot higher after a year
if outpoutches are found in the brain do they ever prophylactically clip them?
yes
what are IADLs?
(It stands for Instrumental Activities of Daily Living)
More advanced ADLs
Example: writing checks or grocery shopping (more than just basic self-care in the home. They require more complex reasoning)
Internal Carotid Artery Syndrome (2)
Massive symptoms
MCA & ACA involved
Details on Recreational Therapist
Recreational Therapist
- Bad part of rec therapy is that they are not reimbursed, so they are usually only in outstanding rehab centers
- They do great things that are more fun
how long can you continue to have cerebral edema
2-3 weeks
How To diagnose a Stroke (4 things - practice thinking of details if you want)
- •History
- •Physical Exam
- •Tests
- blood tests
- clotting time
- CBC
- Urinalysis
- Lumbar puncture
- EKG
- blood tests
- •Imaging
- CT
- MRI
- Ultrasound (dopplar)
- echocardiogram
What are two types of strokes?
which is most common and by how much?
- Thromboembolic strokes: 80% of strokes (most common)
- Hemorrhagic (pts call it an aneurism): 20% of strokes
Imagine the parts of the cerebrum that are supplied by the anterior, middle, and posterior cerebral arteries
what kinds of deficits do strokes cause?
(name two that we shouldn’t forget about)
All kinds of stuff (she had us come up with several, but I couldn’t write fast enough)
Don’t forget autonomic functions
Proprioception
What are some different areas of stroke? (4)
Different areas of stroke
- Anterior Cerebral Artery
- Posterior Cerebral Artery
- Middle Cerebral Artery
- Homunculus
what is done for aneurisms (hemmorhagic strokes)?
What do they do with aneurysms?
- surgery - clip it
- metal clips that stay in there
What is the actronym taught for stroke detection to the general public?
What does it mean?
FAST acronym
- face
- look for drooping on one side
- arms
- look for one lagging when held out
- speech
- slurred
- time
- can use clot-buster if caught in time (I think 1 hour window)
what is a uniqe problem of hemorrhatic strokes?
Blood getting into the brain can also cause its own problems