Patho Chap 3 Flashcards

1
Q

Tay Sachs

A

Inherited lososomal storage disease where the infant is unable to break down glycoproteins

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2
Q

Peroxisomes

A

Smaller than lysosomes, they degrade long fatty acid chans. Acetyl CoA is made from fatty acids by perioxisiomes

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3
Q

Methods of Chemical Signaling

A

3 Gap Junctions, Receptors and Release of signal molecules

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4
Q

Gap Junctions

A

Cardiac cells communicate this way. AP’s are transmitted directly from one cell to the next

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5
Q

Receptors

A

Signal molecule binds to the receptor site

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6
Q

Release of signal molecules

A

Ex. Inflamatory Response

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7
Q

Methods of Cellular Communication

A
  1. Hormonal Signaling, Neuro Hormonal Signaling, Paracrine Signaling, Autocrine Signaling
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8
Q

Hormone Signaling

A

Hormone travles through blood or Lymph. Ex. Insulin

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9
Q

Neurohormonal Signaling

A

Hormones are released into the blood by neurosecretory neurons. Ex. ADH is produced by the Hypothalamus then transmitted along axons and stored in the pituiatry

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10
Q

Paracrine Signaling

A

Cells secrete signaling molecules to nearby cells

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11
Q

Autocrine Signaling

A

Molecules act back on the cell of origin

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12
Q

Adenylyl Cyclase is converted to what by the G protein

A

cAMP

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13
Q

2 common second Messengers

A

cAMP and Ca++

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14
Q

Phases of Cellular Respiration

A
  1. Digestion 2. Glycolosis 3. Citric Acid Cycle
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15
Q

Products of Glycolosis

A

2 pyruvic Acid 2 NADH 2 ATP

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16
Q

If inadequate O2 available to what and where is pyruvic acid converted

A

Converted to lactic acin in the Liver

17
Q

Products of Citric Acid Cycle

A

1 GTP, 3 NADH 1 FADH2

18
Q

How many ATP are produced from Glycolosis (anerobic)

A

2 net ATP

19
Q

How many ATP are produced from Oxidative Phosphorilation (aerobic)

A

26 NET 2.5 ATP per NADH and 1.5 ATP pre FADH2

20
Q

Normal Plasma Osmolality

A

280- 294 mOsm/ kg

21
Q

Osmolality is measured in?

A

Kg Weight

22
Q

Osmolarity is measured in

A

L Volume

23
Q

How much of the electrochemical gradient is caused by the Difference in Na and K

A

80%

24
Q

How much of the electrochemical gradient is caused but the Na/K pump

A

20%

25
Q

Normal K in the cell

A

150 mEq/ L

26
Q

Notmal K outside the cell

A

5 mEq/ L

27
Q

Normal Na in the cell

A

14 mEq/L

28
Q

Normal Na outside the cell

A

140 mEq/L

29
Q

Phases of the Cell Cycle

A

Interphase –> Mitotic Phase –> Cytokinesis

30
Q

Steps of the Interphase

A

G0 –> G1 –> S –> G2

31
Q

Steps of the Mitotic Phase

A

Prophase –> Metaphase –> Anaphase –> Telophase