Path outline final (KP) Flashcards
What is a severe case of diffuse destruction of brain w/ no cerebral hemispheres called?
Hydranencephaly
Is the stroma destroyed in Hydranencephaly?
Yes
What is Congenital Hydranencephaly associated with?
Examples?
Cerebrum
Fetal viral infxns
Ex: Calves BVD & prego Sheep (Blue Tongue) vax at day 50-58
What is a typical lesion of hydranencephaly?
Absence of Telencephalon w/ complete or almost complete absence of cerebral hemispheres
Hydrancephaly: On necropsy what would you see in the cranial cavity?
Membranous sac of CSF made up of enclosed leptomeniges inside a complete cranial cavity
Hydrancephaly: What would the skull look like?
Mostly normal but could have mild doming & thickening of cranial bones
Is there an epindymal lining with Hydranencephaly?
NO
What viruses are associated with Hydrancephaly?
Akbane Bluetounge RVF Wessel-bron BVD Border Dz
If Porencephaly occurs prenatal what will the brain look like?
Focal destruction of White Matter w/ caveated cysts in the cerebral hemisphere
What is Porencephaly?
A congenital anomaly that effects the White Matter of the Cerebrum
How do the the cysts in Porencephaly appear and what are they filled with?
Smooth walled & filled with clear fluid
Associated viruses of Porencephaly?
Border Dz
BVD
What deficiency is associated with Porencephaly?
CU deficiency
What is Internal Hydrocephalus?
Abnormal accumlulation of CSF ventricles
What is External Hydrocephalus?
Abnormal accumulation of CSF in the Subarachnoid Space
Is Stroma present in Hydrocephalus?
YES
What can cause Congenital Hydrocephalus?
Idiopathic
Viral
Nutritional Deficiency
What are the lesions of Congenital Hydrocephalus? TQ
Lateral ventricular distention w/ domed shaped, thin boned ENLARGED cranium
What animals are more prone to congenital hydroencephalus?
Dogs-Brachycephalic
Calves
Foals
Pigs(familial)
What can cause Acquired Hydroencephalus?
Anything that Obstructs the flow of CSF leading to pressure atrophy.
Progressive dz
What are the lesions of Aquired Hydroencephalus? TQ
Lateral ventricular distention with NO cranial malformation
Lipping is present
What is Acquired Hydroencephalus a sequele of?
Bacterial meningitis Granulomatous meningitis (TB) FIP Cryptococcosis Intracranial Neoplasms Parasitic cysts Cholestratoma (horse)
What is Abiotrophy?
“Cerebellar Atrophy”
Premature apoptosis of Cerebellum
What is the primary metabolic defect/degeneration of the Cerebellum? TQ
Abiotrophy
Happens after the cerebellum has reached full size