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Cellular Science > Past Questions > Flashcards

Past Questions Flashcards

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Biology 101 flashcards
1
Q

What dictiates the biological function of heparan sulphide?

Level and sulphation patterns of the way it’s attached to the core protein

A

Levels and sulphation pattern

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2
Q

What is the key feature of hodgekins syndrome lymphoma as opposed to non-hodgekins

A

Presence of Reed-Sternberg cells (mature malignant B-lymphocytes) (multinucleated or bi-lobed)

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3
Q

True or false: MPS 1 Hurlers is an autosomal dominant inherited disease

A

False: autosomal recessive

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4
Q

What is aneuploidy

A

Abnormal amount of chromosomes

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5
Q

In histology, how would you test for presence of acid-fast bacilli for TB

A

Ziehl Nielssen stain

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6
Q

True or false: incidence for CF in Caucasian people is 1 in 25

A

False

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7
Q

Describe the characteristics of adipose tissue

A

Loose connective tissue
Characteristic of conn tissue
Types: white and brown
Functions: energy, insulation, cushioning

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8
Q

Describe the characteristics of reticular tissue

A

?

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9
Q

Describe what the typical neuropathological hallmark of Parkinson’s disease

A

Lewy bodies found in the

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10
Q

What is prevalence

A

Usually expressed as a fraction, as a percentage or as number of cases per 10,000 or 100,000 people

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11
Q

Describe the difference between a sarcoma and carcinoma

A

?

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12
Q

Characteristics of a sarcoma

A

?

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13
Q

Characteristics of a blastoma

A

?

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14
Q

What is a hereditary risk factor for venous thrombosis

A

Factor 5 Leiden

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15
Q

When was the NHS cervical screening programme formally set up

A

1988

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16
Q

What is a benign tumour

A

A localised tissue of origin

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17
Q

State a pathology of connective tissue

A

Malignant melanoma, chondroma

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18
Q

What type of tissue is blood

A

Connective

19
Q

What is the function of connective tissue

A

Cushioning and physical support

20
Q

Where is transitional epithelia present

A

UT

21
Q

Epithelial tissue is characterised by

A

Little extra cellular matrix (ECM)

22
Q

Cirrhosis is defined as irreversible replacement of liver tissue by?

A

Collagen

23
Q

What is caused by a mutation at the q31.2 locus of chromosome 7

A

Cystic fibrosis

24
Q

True or false: pneumoconiosis is a Chronic Obstructive Pulmonary Disease

A

False

25
Q

What is the optimal pH for lysosomal functioning

A

pH 4.5

26
Q

What is the genetic inheritance pattern of MPS IIIA hurler

A

Autosomal recessive

27
Q

Storage of heparan sulphate leads mainly to which phenotype in an MPS IIIB patient

A

Brain dysfunction

28
Q

MPS I is caused by the lack of which enzyme?

A

a-L-Iduronidase

29
Q

Which of the following surrounds each bundle of muscle fibres

A

Epimysium

30
Q

Dychennes muscalar dystrophy is characterized by absence of which hormone

A

Dystropin

31
Q

What are two infectious forms of dementia

A

Kuru

Frontotemporal dementia

32
Q

Lewy bodies are a pathological hallmark of which disease

A

Parkinson’s

33
Q

What are the most commonly used stains in non-gynaecology Cytology

A

Papanicolaou and giesma

34
Q

Nepgrotic syndrome is characterised by?

A

Oliguria

35
Q

True or false: immune complexes are a common feature ADPGN

A

False, compliment only

36
Q

ADPGN is usually preceded by what

A

Streptococcal infection

37
Q

Nephritic syndrome results from?

A

Disturbances in glomerular structure

38
Q

The number oocytes (eggs) a woman has is referred to as her:

A

Ovarian Reserve

39
Q

An audit following a sample through the laboratory is called

A

Sample audit

40
Q

True or false: discussing he outcome of the audit is part of the clinical audit cycle

A

False

41
Q

True or false: the HCPC promotes professional education and training

A

False: set standards of proficiency

42
Q

How many layers does the ethical grid have

A

4

43
Q

What is a vertical audit

A

A sample through a process from beginning to end

Cellular Science (19 decks)

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