Past paper questions Flashcards

1
Q

A 3-year-old boy is brought to the paediatric emergency department by his father. His father is concerned as he has developed a pinprick purple rash on the back of his legs and has been complaining of stomach and knee pain for the last few days. Prior to this, he had a cold.

His vital signs are normal.

Which of the following is the next most appropriate step of management?

Steroids

Non-steroidal anti-inflammatory drugs (NSAIDs)

Antibiotics

Anti-hypertensives

Intravenous Fluids

A

Non-steroidal anti-inflammatory drugs (NSAIDs)

This is a case of Henoch-Schonlein purpura (HSP). It commonly presents with a triad of purpura/petechiae on the buttocks and lower limbs, abdominal pain and arthralgia. Other features include haematuria, proteinuria, pyrexia and hypertension.

The majority of HSP cases are self-limiting and resolve completely. Therefore, simple analgesia such as NSAIDs and/or paracetamol can be used. In severe cases, steroids may be indicated. If hypertension is present, antihypertensives may also be indicated.

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2
Q

A 3 year old girl is brought to the GP by her mother. She has had a cold for the last few days, but now developed a rash on her chin. It blanches under pressure, but her mother remains worried about the cause. She was previously well and is up to date with all scheduled immunisations. On examination the girl has a fever of 38.5 degrees Celsius, with a maculopapular rash around her mouth, ulcerations on her tongue and blisters on the palms of her hands and the soles of her feet. There are no signs of excoriation.

Which of the following is the most likely cause of her symptoms?

Hand, foot and mouth disease

Scarlet fever

Slapped cheek syndrome

Meningococcal septicaemia

Measles

A

hand foot and mouth

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3
Q

A 3-day-old neonate presents to paediatric A&E with his concerned parents. He was born at 39+2 weeks following spontaneous vaginal delivery, and was discharged from hospital yesterday evening after being established on bottle feeding. His parents are worried as this morning he vomited a large quantity of bile stained vomitus. He is still yet to pass meconium. On examination of the abdomen, distension is noted, but there are no palpable masses.

Which of the following is the most likely diagnosis?

Meconium Ileus

Pyloric Stenosis

Necrotising Enterocolitis

Intestinal Malrotation

Viral Gastroenteritis

A

Meconium Ileus

This is the correct answer. Meconium ileus typically presents in the first few days of life as a delay in passing meconium (> 48 hours) and features of bowel obstruction (bilious vomiting). Diagnosis is confirmed with abdominal x-ray which shows characteristic findings of a ‘bubbly’ appearance of the intestines and lack of air-fluid levels

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4
Q

A 3-day-old neonate presents to paediatric A&E with his concerned parents. He was born at 39+2 weeks following spontaneous vaginal delivery, and was discharged from hospital yesterday evening after being established on bottle feeding. His parents are worried as this morning he vomited a large quantity of bile stained vomitus. He is still yet to pass meconium. On examination of the abdomen, distension is noted, but there are no palpable masses.

Which of the following is the most likely diagnosis?

Meconium Ileus

Pyloric Stenosis

Necrotising Enterocolitis

Intestinal Malrotation

Viral Gastroenteritis

A

Meconium Ileus

This is the correct answer. Meconium ileus typically presents in the first few days of life as a delay in passing meconium (> 48 hours) and features of bowel obstruction (bilious vomiting). Diagnosis is confirmed with abdominal x-ray which shows characteristic findings of a ‘bubbly’ appearance of the intestines and lack of air-fluid levels

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5
Q

A 3 year old boy is brought to the GP because he has a rash and red eyes.

His mother says her son developed a non-productive cough, runny nose and red eyes about 4 days ago, and this morning he woke up with a red blotchy rash over his head and face which has since spread onto his chest and arms. His mother also noted white spots in his mouth a few days ago. He is normally healthy. He takes no medicines and has never had any vaccinations, as his parents do not think they are safe.

On examination, the boy appears unhappy but well. His saturations are 99% in air, respiratory rate is 20, heart rate is 82 and capillary refill time is 2 seconds. His temperature is 39.5 degrees. There is an erythematous maculopapular rash across his head, neck, torso and limbs.

What kind of vaccine would have prevented this child’s infection?

Toxoid vaccine

Live attenuated vaccine

Killed vaccine

Conjugate vaccine

Polysaccharide vaccine

A

Live attenuated vaccine

This unvaccinated child with cough, coryza and conjunctivitis, white spots in the mouth and a rash should raise suspicion for measles infection. Measles is routinely vaccinated against with the MMR, which is a live attenuated vaccine

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6
Q

A 27 year old lady who is 32 weeks pregnant visits her GP concerned about breastfeeding. Which of the following situations would be acceptable for her to breastfeed?

Taking ibuprofen for back pain

Neonatal galactosaemia

Herpes simplex lesions on the mother’s breasts

Maternal HIV infection (viral load undetectable)

Maternal multi-drug resistant tuberculosis infection

A

Taking ibuprofen for back pain

Ibuprofen is considered safe for breastfeeding infants as only very small quantities appear to be excreted into breast milk after maternal ingestion. Furthermore, it is considered to be one of the analgesics of choice in breastfeeding mothers

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7
Q

methylphenidate same as

A

ritalin

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8
Q

A 10 year old boy with a diagnosis of attention-deficit hyperactivity disorder (ADHD) attends the outpatient psychiatry clinic for review. He was recently started on Methylphenidate to control his symptoms. His behaviour has improved, however, he has developed facial tics which he finds distressing.

Which of the following is the most appropriate drug to switch to for long-term management of his condition?

Melatonin

Sertraline

Ritalin

Risperidone

Atomoxetine

A

Atomoxetine

Atomoxetine is another stimulant medication. It is recommended for ADHD refractory to Methylphenidate or in those who it is not appropriate due to risk factors or development of side effects. Development of facial tics is an indication to change medications

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9
Q

An eight year old girl is brought into the emergency department by ambulance. She was found by her mother minimally responsive and with vomit in her mouth. On examination, she is somnolent but rousable, with a GCS of nine. Observations were normal. Her mother reports that she had been unwell with a ‘cold’ over the last three days, and her mother had given her aspirin and ibuprofen for her headache and fever. Blood tests showed a mild anaemia, a transaminitis, raised bilirubin, a prolonged international normalised ratio, raised lactate and a raised C-reactive protein. A toxicology screen is negative. What is the most likely diagnosis?

Viral encephalitis

Reye’s syndrome

Unintentional overdose

Meningococcal meningitis

Head injury

A

Reye’s syndrome

Aspirin should not be given to children under 12 years old because of its association with Reye’s syndrome. Reye’s syndrome is acute liver failure and non-inflammatory hepatic encephalopathy which occurs in children under 12 who are given aspirin during the acute phase of a viral infection. Liver biopsies show microvesicular steatosis and venous collapse. Treatment is supportive, and often requires ITU admission. Lactulose can be used to lower ammonia levels

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10
Q

when is jaundice normal in neonates

A
  • after 24 hours
  • jaundice is not normal if apparent within the first 24 hours of life

Neonatal jaundice is common. Most cases are physiological, however it is important not to miss serious pathology. Any jaundice in the first 24 hours of life is always pathological.

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11
Q

causes of jaundice in <24hrs

A
  • Haemolytic disorders (Rhesus incompatibility, ABO incompatibility, G6PD, spherocytosis)
  • Congenital infection (TORCH screen is indicated)
  • Sepsis
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12
Q

causes of jaundice in >24hrs

A

Physiologic jaundice
Breast milk jaundice
Dehydration
Infection, including sepsis
Haemolysis
Bruising
Polycythaemia
Crigler-Najjar Syndrome

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13
Q

causes of jaundice >14 days

A

Physiologic jaundice
Breast milk jaundice
Infection
Hypothyroidism
Bililary obstruction (incl. biliary atresia)
Neonatal hepatitis

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14
Q

A 2-week old neonate, born prematurely at 30 weeks’ gestationn, has had 2 days of vomiting and 1 day of bloody stools. The vomiting has occasionally been streaked with green, and occurs particularly after feeding with expressed breast milk. The stool has also been streaked with fresh red blood.

The baby has also significantly deteriorated over the last few days, and has required IV fluids and has just been re-intubated for the first time since day 2 of life.

On examination, the baby’s abdomen is significantly distended. An abdominal X-ray shows distended loops of bowel with thin black lines within the white bowel walls.

What is the most appropriate management for this condition?

Cow’s milk formula

Cooling to 34 degrees

Retinal laser therapy

Broad spectrum antibiotics and parenteral nutrition

Surgical resection of ectopic gastric mucosa

A

necrotising enterocolitis

Broad spectrum antibiotics and parenteral nutrition

This premature infant with bile-streaked vomiting, blood-streaked stool, abdominal distention and intramural air on abdominal x-ray has necrotising enterocolitis. The best initial management of necrotising enterocolitis is broad spectrum antibiotics and parenteral nutrition to prevent infection and rest the bowel

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15
Q

A 13 year old boy presents to the GP because his mum is worried that he has recently been ‘going blue’. Friends and family have commented that he looks a bit blue. On questioning, he reports feeling a little short of breath when playing football, but otherwise reports feeling well. His mother says he has no known conditions apart from a hole in the heart that was mentioned early on but was never followed up on.

On examination, he appears moderately cyanotic. He has clubbing of the fingernails. There is a harsh holosystolic murmur loudest at the lower left sternal edge. The lung fields are clear to auscultation. His oxygen saturations are 93%, respiratory rate is 18, heart rate is 80, and temperature is 36.8.

What is the most likely underlying cause of this patient’s colour change?

Reversal of direction of cardiac shunting

Narrowing of the aorta

Lead exposure

Reversible constriction of bronchioles

Abnormal insertion of the pulmonary veins

A

Reversal of direction of cardiac shunting

Eisenmenger syndrome describes the reversal of a left-to-right shunt (patent ductus arteriosus, atrial septal defect, or ventricular septal defect) to a right-to-left shunt

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16
Q

A neonate is delivered by emergency caesarean section at 32 weeks gestation after preterm premature rupture of membranes. At 1 minute after birth, the neonate appears blue at the fingers and around the mouth and has a poor respiratory effort. The baby is resuscitated, intubated and stabilized before transfer to the neonatal intensive care.

At 48 hours after delivery, the baby appears moderately cyanotic and is grunting on inspiration. The baby has a raised respiratory rate, nasal flaring and subcostal recessions. A chest X-ray shows a ground glass appearance to the lung field bilaterally.

Which of the following medicines given to the mother prior to delivery could help reduce the severity of this neonatal condition?

Dexamethasone

Misoprostol

Pethidine

Magnesium sulphate

Prostin gel

A

Dexamethasone

This preterm baby with signs of respiratory distress including cyanosis, grunting, tachypnoea, nasal flaring and subcostal recessions with a ground glass appearance on chest x-ray has neonatal respiratory distress syndrome. If preterm delivery is suspected, maternal intramuscular steroid injection, such as dexamethasone, can help to boost foetal surfactant production and thus reduce the likelihood of developing neonatal respiratory distress syndrome

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17
Q

A 6 month old baby boy is an inpatient on a paediatric hospital ward for a chest infection. He has been sleeping quietly in his cot but when a nurse checks on him, he is unresponsive and looks blue. The nurse ensures that it is safe to approach him, calls for help and keeps his airway in a neutral position. The nurse looks for chest movements and listens for breath sounds, observing infrequent, noisy gasps, less than once every 3 seconds. She cannot feel a pulse.

Which of the following is the most appropriate action for the nurse to take?

Give 15 chest compressions followed by 2 rescue breaths

Give 5 rescue breaths followed by 15 chest compressions

Feel longer for a pulse

Observe in case he stops breathing

Give 2 rescue breaths followed by 15 chest compressions

A

Give 5 rescue breaths followed by 15 chest compressions

In paediatric resuscitation, 5 rescue breaths are given initially. As opposed to adult basic life support, rescue breaths are given before chest compressions in children and this is one of the key differences to increase the amount of circulating oxygen in the body

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18
Q

A 6 week old baby boy is brought to A&E as a GP referral because he is still yellow.

He has been getting progressively more yellow for the last 3 weeks. His mum says his poo has also changed from thick black when he was born to mustardy to chalky. His wee has also turned a dark yellow. Otherwise, he has been breastfeeding well and is growing along his centiles. He was born at 39+6 by spontaneous vaginal delivery after a normal pregnancy. Antenatal screening and scans showed no abnormalities.

On examination, the baby appears well. His abdomen is soft and a liver edge is palpable 2cm below the costal margin. Antenatal screening and scans were all normal. Blood tests show a significantly raised ALT, ALP and bilirubin (predominantly conjugated).

What is the most likely underlying cause of this baby’s presentation?

Haemolysis from enzyme deficiency

Maternal antibody

Liver viral infection

Fibrosis of biliary tree

Abnormal erythrocyte membrane

A

Biliary fibrosis - biliary atresia
This infant with prolonged jaundice, dark urine, chalky-white stool and conjugated hyperbilirubinaemia is suspicious for an obstructive cause of jaundice. The results of the hepatic scintigraphy radioisotope scan (highlights the liver and not the bowel) is suspicious for biliary atresia. Biliary atresia is characterized by progressive fibrosis and destruction of the biliary tree

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19
Q

A 15 month old child has a history of epilepsy and has difficulty walking. The gait of the child is ‘scissor walking’. The mother reports that the labour was complicated by shoulder dystocia. The APGAR score at birth was 4 and the neonate required a stay in the neonatal intensive care unit (NICU) for a few days. What is the most likely location for the pathology seen in this presentation?

Hip injury at delivery

Cervical nerves

Periventricular

Basal ganglia

Congenital developmental dysplasia of the hip

A

Periventricular

Periventricular damage (due to a hypoxic ischaemic event during a prolonged delivery due to the baby getting stuck) is the aetiology behind spastic diplegia. The gait is classically termed as scissor walking

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20
Q

A 3 year old girl is brought to the GP by her mother. She has had a cold for the last few days, but now developed a rash on her chin. It blanches under pressure, but her mother remains worried about the cause. She was previously well and is up to date with all scheduled immunisations. On examination the girl has a fever of 38.5 degrees Celsius, with a maculopapular rash around her mouth, ulcerations on her tongue and blisters on the palms of her hands and the soles of her feet. There are no signs of excoriation.

Which of the following options is the most likely pathogen responsible for her symptoms?

Measles virus

Parvovirus B19

Coxsackie virus A16

Streptococcus pyogenes

Staphylococcus aureus

A

Coxsackie virus A16

This girl presents with features in keeping with hand, foot and mouth disease, most commonly caused by enteroviruses such as Coxsackie virus A16

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21
Q

A 2-year-old girl comes to the GP with her parents. Her parents are concerned she is having difficulty growing. They say that over the past month she has felt tired and lethargic, and has intermittent diarrhoea. His growth chart shows she has dropped from the 75th centile for height and weight to the 25th centile in the last 6 months. On examination there is a vesicular rash on the child’s knees. Her doctor suspects coeliac disease.

Which of the following would be the next most appropriate investigation?

Duodenal biopsy

Faecal calprotectin

Anti-gliadin antibody

Endomyseal antibodies

Tissue transglutaminase (TTG) antibodies and total IgA

A

Tissue transglutaminase (TTG) antibodies and total IgA

This is correct. The growth difficulties along with abdominal distension and diarrhoea are suggestive of coeliac disease. The rash described is most likely dermatitis herpetiformis, which is strongly associated with the condition. The next best investigation would be to look measure anti-TTG levels (raised in coeliac disease), as well as total IgA, because IgA deficiency could lead to a false negative result

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22
Q

A 10-year-old girl was admitted to a paediatric ward 3 days ago due to an acute exacerbation of asthma. At the time of admission, she is very short of breath and could not complete sentences fully. On auscultation, a silent chest is noted. Her peak expiratory flow rate was 100 l/min (35% of normal), and oxygen saturations were 93%.

Which of the following features make this a life-threatening acute exacerbation of asthma?

Inability to complete sentences

Silent chest

Her peak expiratory flow rate

Shortness of breath

Her oxygen saturations

A

Silent chest

This is correct. Silent chest occurs because of bronchoconstriction so severe that there is not enough air movement to produce even an audible wheeze. This is a life-threatening sign and the child must be taken to hospital immediately. Other signs of a life-threatening attack include cyanosis, poor/no respiratory effort, peak expiratory flow rate <33%, hypotension and an altered level of consciousness

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23
Q

A 14-year-old girl with Turner syndrome is found to have an ejection systolic murmur heard loudest posteriorly between the shoulders.

Given the most likely diagnosis, which of the following signs would most likely be seen on examination?

Radio-femoral delay

Cyanosis

Palpable thrill

Tachypnoea

Malar flush

A

Radio-femoral delay

This patient likely has coarctation of the aorta, due to the typical murmur and the association with Turner syndrome. Radio-femoral delay is caused by the collateral circulation via the chest wall delaying bloodflow to the lower extremities.

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24
Q

An 11 year old boy presents to his GP complaining of a three day history of right hip pain. There is no history of trauma. His mother reports that the family is recovering from a common cold. On examination, there is restricted internal rotation and extension of the right hip. He does not have a temperature and his past medical history is unremarkable. His height and weight are at the 50th percentile for his age and his immunisations are up to date. What is the most likely diagnosis?

Hip fracture

Slipped femoral epiphysis

Transient synovitis

Tuberculosis arthritis

Perthe’s disease

A

Transient synovitis

Transient synovitis is an inflammation in the hip joint that causes pain, limp and sometimes refusal to bear weight. This occurs in pre-pubescent children and is the most common cause of hip pain. It occurs when a viral infection, such as an upper respiratory infection, moves to and settles in the hip joint. Limited range of motion, specifically extension and internal rotation of the hip can be found. It is confirmed using a hip x-ray (which will be normal) and ultrasound which shows synovitis. It is treated using NSAIDs and bedrest for up to 6 weeks

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25
Q

Perthe’s disease

A

Perthe’s disease is most common in children from 3-11 years of age. It presents as a progressive reduction in movements in all ranges over a period of months. It is confirmed using x-rays of the hip, which show reduction of joint space and decreased size of the femoral head. An ultrasound can show synovial thickening. Management involves NSAIDs, analgesics and physiotherapy. Surgery may be needed to correct the femoral head defect

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26
Q

Perthe’s disease

A

Perthe’s disease is most common in children from 3-11 years of age. It presents as a progressive reduction in movements in all ranges over a period of months. It is confirmed using x-rays of the hip, which show reduction of joint space and decreased size of the femoral head. An ultrasound can show synovial thickening. Management involves NSAIDs, analgesics and physiotherapy. Surgery may be needed to correct the femoral head defect

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27
Q

Slipped femoral epiphysis

A

Slipped femoral epiphysis most commonly presents in obese adolesent children with pain over the front of the thigh, knee and groin, evolving over minutes to weeks. There is limitation of flexion, abduction and medial rotation. Pain is associated with exercise. Investigations include a lateral x-ray of the hip, looking for displacement of the growth plate. Management includes treatment of the underlying condition, most commonly primary hypothyroidism. In this case the patient is slightly young and not obese which makes SUFE less likely

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28
Q

A mother brings in her 12-year-old son to paediatric A&E because he has been complaining of a headache since this morning. He complains that the lights in the hospital are hurting his eyes and says his neck feels stiff. On examination there is a purpuric rash across the child’s chest and torso. His temperature is 38.0ºC, he has a heart rate of 120/min, a respiratory rate of 26, and a blood pressure of 90/65 mmHg. Which of the following is the most likely diagnosis?

Meningococcal septicaemia

Henoch-Schonlein Purpura

Tension-type headache

Migraine

Measles

A

Meningococcal septicaemia

This is correct. This child has presented with classic symptoms of meningitis (neck stiffness, photophobia, headache) as well as sepsis (tachycardia, tachypnoea, hypotension, petechial rash), known as meningococcal septicaemia. This patient requires urgent intravenous antibiotics

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29
Q

A 3-year-old girl is brought to the GP by her parents. For the past four days she has had a fever, runny nose, cough and non-bloody diarrhoea. Last night, her parents noticed that she had developed a pink rash on her legs and arms. She is normally fit and well and is up to date with all her vaccinations. On examination, a pink lace-like rash is visible on all four of her limbs, along with erythematous patches on her cheeks which feel hot to touch.

Which of the following is the most likely pathogen causing her symptoms?

Rhinovirus

Coxsackie Virus A16

Measles

Parvovirus B19

Human Herpes Virus 6 (HHV6)

A

Parvovirus B19

This is the correct answer. This child has presented with a prodrome of fever, coryzal symptoms and diarrhoea, followed by the onset of a diffuse ‘lace-like’ rash across the body and characteristic bright red cheeks. This presentation makes parvovirus B19, aka slapped-cheek syndrome, the most likely diagnosis

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30
Q

A 9-week-old boy is seen in the Paediatric Assessment Unit with a 2-week history of worsening projectile vomiting after feeds.

On examination, there is a smooth spherical mass in the left upper abdomen, approximately the shape of an olive.

Which of the following acid–base abnormalities would most likely be seen on a blood gas?

Hyponatraemia

Hypokalaemia

Hyperchloraemia

Metabolic acidosis

Respiratory alkalosis

A

Hypokalaemia

Severe pyloric stenosis can lead to hypochloraemic hypokalaemic metabolic alkalosis due to excessive vomiting - so hypokalaemia may be present.

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31
Q

A 7-year-old boy presents to the Emergency Department with increasing fatigue and drowsiness, on a background of 5 days of diarrhoea and vomiting. There is no blood or mucous in his stool, but his urine has become significantly darker. His mother notes that in the last 24 hours he has been unable to eat any solid food, but, he can tolerate small amounts of fluid.

He is diagnosed with gastroenteritis and his dehydration deficit is calculated to be 5%. His healthy weight is approximately 25kg.

Which of the following is the correct volume of total fluids to prescribe over 24 hours?

1600 ml

3200 ml

1250 ml

2850 ml

750 ml

A

2850 ml

This is the correct answer. Using the paediatric fluid formula (10 x 100) + (10 x 50) + (5 x 20), the maintenance fluid required for this 25kg child is 1600ml over 24 hours.

The deficit that needs to be replaced is calculated using the formula weight (kg) x 10 x % dehydration (5%), which comes to 1250ml.

1600ml + 1250ml = 2850 ml.

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32
Q

A 5 year old boy is brought to the GP by his mother. He has been feeling generally unwell over the last 2 days with lethargy, headache, sore throat, runny nose and fever. He was previously well and is up to date with all scheduled immunisations. He has developed an erythematous rash on his torso and both cheeks, which blanches under pressure. His tongue and buccal mucosa appear normal.

Which of the following is the most appropriate advice to give his mother about the risk of passing the infection to other children?

He may still be infectious after several weeks and should be not return to school

He will remain infectious until 4 days after the rash resolves

He will remain infectious until the rash has crusted over

He is no longer infectious and can return to school

He will remain infectious until 24 hours after the first dose of antibiotics

A

He is no longer infectious and can return to school

This boy presents with features in keeping with slapped cheek syndrome. Once the rash appears, children are no longer infectious

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33
Q

A 13-year-old patient attends a Child and Adolescent Mental Health Service (CAMHS) clinic with symptoms of low mood, reduced energy levels and anhedonia over the past year. There are no features of psychosis and the patient denies any thoughts of deliberate self harm.

Alongside talking therapies and lifestyle changes, which of the following antidepressants is most appropriate to prescribe?

Venlafaxine

Citalopram

Sertraline

Fluoxetine

Mirtazapine

A

Fluoxetine

Fluoxetine, a selective-serotonin-reuptake inhibitor, is the only antidepressant medication licensed for children and has the best evidence base for use in children.

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34
Q

A junior doctor is asked to review a neonate on the postnatal ward. He was born 10 hours ago and has suddenly turned blue and developed an increased work of breathing. Upon examination, he has central cyanosis, he is not tachypnoeic, there are no additional breath sounds, and on auscultation of the heart there are no murmurs. A chest x-ray shows cardiomegaly. He has been given Oxygen by the nurses but this has not improved the cyanosis.

Which of the following is the next best step in the management of this patient?

Alprostadil

Indomethacin

Echocardiogram

Furosemide

Insert nasogastric tube for feeding

A

Alprostadil

This is the correct answer. This is a case of duct dependent congenital heart disease, which is managed with prostaglandins. This is to promote patency of the ductus arteriosus, which begins to close shortly after birth and is the cause of cyanosis in this situation. This will allow the infant to survive long enough to allow investigations to confirm the diagnosis, which is most likely transposition of the great arteries, and thus surgical correction

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35
Q

A 7 year old boy has been admitted to the PAU after 1 day of vomiting and diarrhoea. His parents are worried that he may have been suffering from food poisoning. He was admitted by the paediatric registrar as he wasn’t able to keep down sips of water. The registrar has started him on suitable antiemetics and has organised a series of investigations in order to establish a possible cause. You are asked to write up suitable full maintenance fluids for the next 24 hours. On reviewing the notes you see that the boy weighs 27kg and there are no concerns about heart failure, DKA or recent trauma. On examination his mucous membranes appear moist and his bloods do not show any electrolyte abnormalities.

What would be the most suitable fluids regimen to start him on for 24 hours full fluids maintenance?

1640ml of 5% dextrose given in bags of 500ml

810ml of 0.9% NaCl given in bags of 500ml and made up with 10mmol KCl per 500ml bag

810ml of 0.9% NaCl + 5% dextrose given in bags of 500ml and made up with 10mmol KCl per 500ml bag

810ml of 5% dextrose given in bags of 500ml

1640ml of 0.9% NaCl + 5% dextrose given in bags of 500ml and made up with 10mmol KCl per 500ml bag

A

1640ml of 0.9% NaCl + 5% dextrose given in bags of 500ml and made up with 10mmol KCl per 500ml bag

36
Q

A 12 month old boy who is currently receiving chemotherapy for acute lymphoblastic leukaemia presents to the GP for routine vaccinations. The mother reports that the boy is currently well with no fevers or recent infections. He has no known food or drug allergies.

On examination, the boy is alert, active and appears well. He has a Hickman line which appears in good condition, with no erythema or tenderness.

Which of the following vaccinations is contraindicated in this patient?

Pneumococcal PCV

Haemophilus influenzae

Meningitis

Measles, Mumps and Rubella (MMR)

Influenza (injected)

A

Measles, Mumps and Rubella (MMR)

37
Q

A 12 month old boy who is currently receiving chemotherapy for acute lymphoblastic leukaemia presents to the GP for routine vaccinations. The mother reports that the boy is currently well with no fevers or recent infections. He has no known food or drug allergies.

On examination, the boy is alert, active and appears well. He has a Hickman line which appears in good condition, with no erythema or tenderness.

Which of the following vaccinations is contraindicated in this patient?

Pneumococcal PCV

Haemophilus influenzae

Meningitis

Measles, Mumps and Rubella (MMR)

Influenza (injected)

A

Measles, Mumps and Rubella (MMR)

38
Q

sources of fever

A

otitis media
viral illness:
- viral exanthum e.g. measles
- sesonala influenza
- covid-19
uti
meningitis
pneumonoa
cellulitis
sepsis

39
Q

how to screen if a chuld is unwell

A

A to E
- RR is the most important first sign to look for

40
Q

PEWS

A

nursing/parent concern
RR
resp distress
oxygen
heart rate
level of cosncpusness

not temp or BP

41
Q

point of care tests - remember

A

capillary blood gas
blood glucose
urine dipstix
nasopharngeal aspirate e.g. flu, cobid rsb

42
Q

lications. ofotitits media

A

hearing loss
balance problem
perforation
mastoiditis
venous sinus thrombosis

43
Q

maculopapular rashes

A

roseola infantum
slapped cheek
meqsles (cough, coryza, conjuncitvitis)
scarlet fever

44
Q

vesicular rahses

A

chicken pox - herpes varicella zoster
hand foot and mouth disease
herpes simplex virus- herpes 1
erythema multiform- herpes 1

45
Q

petechial (<2mm)/ pupuric (>2mm) rash

A

Non blanching
- meningococcal
- Henoch-Schönlein purpura (HSP) - lower limbs due to gaviravity

46
Q

paediatric sepsis six

A
47
Q

management of possible sepsis

A
48
Q

management of possible sepsis

A
49
Q

kawasaki

A
  • One of the most common vasculitides in children; also occurs in adults.
  • Acute self-limiting an acute self-limiting inflammatory disorder affecting predominantly medium sized arteries, particularly coronary arteries causing aneurysms in 15-25% if untreated.
  • Commonest causes of acquired heart disease in children in developed countries.

Presentation
CRASH AND BURN

Management: (no laboratory investigation included in diagnostic criteria):
Systemic inflammation with mild anaemia, leucocytosis with left shirt and thrombocytosis (end of week 2).
Raised ferritin (acute phase reactant). Needs ECG, CXR and cardiac ECHO.
Treatment: IV Ig; Aspirin - high dose in acute phase followed by low dose maintenance.

50
Q

viral vs bacterial meningitits

A

viral:
- entervorus
- herpes virus

bacterial
- younger: Neisseria meningiditis (meningococcal), E.coli, Group B strep
- adults: Haemophilus influnzae and streptococcus pneumoniae

51
Q
A

neisseria meningiditis

52
Q

cough type. andspecific causes summary

A
53
Q

examples of increased work of breathing

A

Nasal flaring

Expiratory grunting – increase PEEP

Use of accessory muscles - sternomastoids

Retractions – suprasternal, SC and IC

54
Q

features of

A

bacterial
- high fever
- pain- pleurisy
- no whezze

viral
- coryzal
- young
- wheeze

55
Q

features of

A

bacterial
- high fever
- pain- pleurisy
- no whezze

viral
- coryzal
- young
- wheeze

56
Q

summary of LRTI management

A
57
Q

UTI urine dipstix and MCS findings

A
58
Q

management of UTI

A
59
Q

indication for urianry tract Ultrasound

A

Under 6 months with first-time UTI that responds to treatment – US within 6 weeks.

**6 months to 3 years:
**
Atypical UTI- organism
Seriously ill.
Septicaemia.
Failure to respond to suitable antibiotics within 48 hours.
Infection with non-E.coli organisms.
Poor urine flow.
Abdominal mass.
Raised creatinine.

Recurrent UTIs
3 or more UTIs with lower UTI.
2 or more UTIs with acute upper UTI (acute pyelonephritis).
1 episode of acute upper UTI and 1 episode of acute lower UTI.

60
Q

Kocher Criteria for Septic Arthritis

A
61
Q

transient synovitis vs septic arthritis

A
62
Q

differential diagnosis of an autrauamtic limp

A
63
Q

antibiotic prescribing

A
64
Q

antibiotic prescribing

A
65
Q

typical clinical features of croup

A

hoarseness
barking cough
stridor

66
Q

infectious differential for croup

A

Acute epiglottitis
Bacterial tracheitis
Severe LN swelling
Tonsillar abscess
Retropharyngeal abscess

67
Q

non infectious differential for croup

A

Acute laryngeal oedema (allergy)
Inhaled foreign body
Inhalation of smoke or hot fumes
Trauma to throat
Hypocalcaemia
Psychological (VCD)

68
Q

investigations for bronchiolitis

A
  • Naso-pharyngeal aspirate PCR.
  • Blood gas: assess respiratory status.
  • Blood tests: FBC, CRP rarely helpful. U&E to assess hydration.
  • CXR: only to exclude complications.

clinical diagnosis!

69
Q

complications of bronchiolitis

A

Acute: dehydration, lung collapse, pneumonia, respiratory failure.

Chronic: persistent bacterial bronchiti, bronchiolitis obliterans (adenov)
(Scarring and fibrosis of small airways

70
Q

manaagment of bronchiolitis

A
  • supportive: oxygen, nutirtion, IV fluids

NO SALBUTAMOL

71
Q

management of viral induced wheeze

A

-nebulised salbutamol

72
Q

differentials for wheeze

A
73
Q

examples of chronic asthma treatment drugs

A

LTRA- suidical ideation
theophylline- awful drug

74
Q

causes of central cyanosis in neonates

A

Airway obstruction
- choanal atresia
- larygomalacia
- macroglossia
- micrognathia or rethrognathia (Pierre-Robin syndrome)

**Pulmonary
- alveolar capillary dysplasia
- lobar emphysema
- pneumonoa/PE/ pneumo
- perissdtent pulmonary hypertension of newborn
- pulmonary hypoplasia
- resp distress syndrome
- transient tachypnoea of the newborn

75
Q

chonal atresia

A
76
Q

laryngomalacia

A
77
Q

micrognathia (pairee robin sequence)

A
78
Q

congential lobar emphysema

A
79
Q

congenital diaphragmatic hernia

A
80
Q

congneital diaphagmatic hernia

A
81
Q

congenital heart disease presentations at birth

A
82
Q

heart murmurs

A
83
Q

intussusception

A
84
Q

red flags for constipation

A
85
Q

constipation summary

A

: <3 complete stools/week.
Large, infrequent stools (Bristol 3/4).
‘Rabbit droppings’ (Bristol 1)
Overflow soiling: very loose/smelly.
unaware passed.

86
Q

dehyration summary

A