Passmed women's health Flashcards
What are the symptoms of candidiasis in women?
Itching, white curdy discharge, sour milk odour, dysuria, superficial dyspareunia
What are the symptoms of candidiasis in men?
Soreness, pruritis and redness - red glazed plaques and papules on penis
What is the treatment for candidiasis?
Antifungals - fluconazole (oral), clotrimazole (topical)
What is the management of cord prolapse?
Immediate delivery of the foetus by caesarean section, knees to chest position to prevent further prolapse, reducing cord into vagina, use of tocolytics (terbutaline) to stop uterine contractions
What are the haemoglobin cut offs for when women should receive iron therapy?
First trimester: <110g/L
Second/third: <105g/L
Post partum: <100g/L
What is the test for gestational diabetes?
Oral Glucose Tolerance Test
What are the diagnostic thresholds for gestational diabetes?
Fasting glucose > 5.6 mmol/L
2-hour glucose > 7.8 mmol/L
What are the treatment guidelines for gestational diabetes?
If glucose is <7 mmol/L trial diet and exercise changes
If glucose target not met in 1-2 weeks, start metformin
If glucose targets still not met, add short acting insulin
If glucose > 7mmol/L add insulin
What is the typical presentation of genital herpes?
Painful genital ulceration (pruritis), some systemic features, tender inguinal lymphadenopathy
What is the first line investigation for herpes?
NAAT - Nucleic Acid Amplification Test
How do you treat genital herpes?
Saline bathing, analgesia, oral aciclovir for patients with severe symptoms or frequent exacerbations
Which drugs should be avoided in breast-feeding mothers?
ciprofloxacin, tetracycline, chloramphenicol, lithium, benzodiazepines, aspirin, carbimazole, methotrexate, sulfonylureas, amiodarone
What is the first line medical management of post-partum haemorrhage?
IV Syntocinon (Oxytocin) followed by ergometrine
What is the definition of a PPH?
Loss of >500ml blood after a vaginal delivery
How do you manage a PPH?
- ABC approach, lie woman flat, two peripheral cannulae, group and save, commence warmed crystalloid infusion.
- rub uterine fundus, catheterisation
- IV oxytocin, ergometrine, carboprost, misoprostol
If cervical cancer smear test is inadequate, when should the test be repeated?
Within 3 months
If two consecutive inadequate samples - colposcopy
What are the risk factors for ectopic pregnancy?
PID, pelvic surgery, previous ectopic, endometriosis, IUCD, POP, IVF
What are the primary features of syphilis?
Chancre, local lymphadenopathy
What are the secondary features of syphilis?
fever, lymphadenopathy, rash, buccal ‘snail track’ ulcers, warts on genitalia
What are the tertiary features of syphilis?
Gummas (granulomatous lesions of skin and bones), AAA, paralysis
Which contraceptives should be stopped after age 50?
Injectable contraceptives - depo-provera. COCP (for bone mineral density)
How long after exposure should HIV testing be done?
4 weeks - can repeat at 12 weeks
What tests are done for HIV?
HIV antibodies (ELISA and western blot), p24 antigen
Anal-oral sex is associated with the transmission of which STI?
Hepatitis A
What is placental abruption?
When the placenta comes away from the uterine wall - usually occurs at 25 weeks and presents with bleeding and abdo pain
What is vasa praevia?
When the foetal blood vessels run across or near the internal orifice. These can be easily compromised by rupture of the membranes, causing bleeding.
What are the treatment guidelines for endometriosis?
1st line - NSAIDS or paracetamol the POP/COCP
2nd line - GnRH agonist
3rd line - androgens
What is the terminiolgy used to describe the baby’s head in relation to the ischial spine?
Station
0 = at level of ischial spine
-2 = 2cm above
+2 = 2cm below
Which score is used to assess whether induction of labour is required?
Bishop score
What are the methods for induction of labour?
Membrane sweep (finger passed through cervix to separate membranes from decidua), vaginal prostaglandin E2, oral prostaglandin E1, maternal oxytocin infusion, amniotomy (breaking of waters), cervical ripening balloon
What methods of induction should be used based on bishop scoring?
If <6 - vaginal prostaglandins/oral misoprostol
if >6 amniotomy and IV oxytocin
What are the risk factors for hyperemesis gravidarum?
Increased levels of beta-hCG (multiple pregnancies, trophoblastic disease), nulliparity, obesity, family history
When should someone be referred for nausea and vomiting in pregnancy?
- unable to keep down liquids and antiemetics
- ketouria
- weight loss > 5% of body weight
- comorbidity
What are the first line medical treatments for hyperemesis gravidarum?
Antihistamines - cyclizine, promethazine
Phenothiazines - prochlorperazine
Doxylamine and pyridoxine (vitamin B6)
How much folic acid should women at increased risk of neural tube defects take?
5mg (all women should take 400mcg)
Which factors put pregnant women at risk of having a child with neural tube defects?
Previous child with NTD, diabetes mellitus, antiepileptic meds, obese, HIV +ve taking co-trimoxazole, sickle cell
What are the common causes of folic acid deficiency?
phenytoin, methotrexate, pregnancy, alcohol excess
What does the factor V leiden mutation cause?
Activated protein C resistance - predisposes to venous thromboembolism - increases risk of DVT
How soon after delivery can someone start the COCP?
After 3 weeks - due to increased risk of venous thromboembolism. Should not be used in breastfeeding mothers. Absolute contraindication if breastfeeding and <6 weeks postpartum
How soon after delivery can someone start the POP?
Any time postpartum - even when breastfeeding
How soon after delivery can the IUD or IUS be inserted?
Within 48 hours of childbirth or after 4 weeks
What are the potential complications of twin pregnancies?
polyhydramnios, hypertension, anaemia, haemorrhage, prematurity, malformation, cord prolapse
What is the definitive treatment for delayed placental delivery in patients with placenta accreta?
Hysterectomy
What is Sheehan’s syndrome?
postpartum hypopituitarism - reduction in the function of the pituitary gland following ischaemic necrosis due to hypovolaemic shock following birth
How long does it take for the POP to become effective?
2 days, if started after first 5 days of cycle. immediately when taken during first 5 days.
What advice should be given about missed pills for POP?
if < 3 hours late, take pill and continue as normal
if > 3 hours late, take missed pill as soon as possible and use other method of contraception until pill taking has been re-established for 2 days
For Cerazette its 12 hours
What is the definition of menorrhagia?
An amount of blood that the person considers to be excessive
What is the appropriate investigation for a UTI?
Urine dipstick in women < 65 with no risk factors for complicated UTI
Urine culture for women > 65. men, catheterised patients
What are the clinical features of a lower urinary tract infection?
Dysuria, urinary frequency, urgency, cloudy/smelly urine, lower abdo pain, low-grade fever
How much folate should be used in the first 12 weeks of a typical pregnancy?
400ug
How much folate should people at a high risk of having a child who develops a NTD take?
5mg
Which factors put people at high risk of having a child with a NTD?
- If either partner has a NTD, family history, previous pregnancy
- antiepileptic drugs, coeliac disease, diabetes, thalassaemia
- BMI > 30
How long after pregnancy can the contraceptive implant be implanted?
Straight after birth
How long does the contraceptive implant last?
3 years
What are the contraindications of getting a contraceptive implant?
Ischaemic heart disease, stroke, breast cancer, liver cirrhosis, liver cancer
What is adenomyosis?
The presence of endometrial tissue within the myometrium
What are the features of adenomyosis?
Dysmenorrhoea, menorrhagia, enlarged, boggy uterus
What is the management of adenomyosis?
Tranexamic acid to manage menorrhagia, GnRH agonists, uterine artery embolisation, hysterectomy
What are the features of HELLP syndrome?
Haemolysis, elevated liver enzymes, low platelets.
What is the cut off Hb levels for iron supplementation in pregnancy?
115 in non-pregnant women, 110 in 1st trimester, 105 in 2nd and 3rd trimester and 100 after childbirth
Can pregnant women have MMR vaccines?
NO - it is a live attenuated vaccine, it should not be given to pregnant women or women trying to get pregnant (28days before pregnancy)
What is the first line treatment of heavy menstrual bleeding in someone trying to get pregnant?
Tranexamic acid
What should you do if you miss one COCP?
Take the last pill even if it means taking two pills in one day, then carry on as normal - no additional contraceptive protection needed
What should you do if you miss 2 or more COCP in week 1?
week 1: emergency contraception if unprotected sex, take last missed pill, use other protection until they have taken pills for 7 days
What should you do if you miss 2 or more COCP in week 2?
Take last missed pill, no need for emergency contraception
What should you do if you miss 2 or more COCP in week 3?
Finish the pills in current pack and then start a new pack the next day, take the last missed pill
What is the recurrence rate of postpartum psychosis?
25-50%.
0.2% chance of postpartum psychosis in the general population
What percentage of women experience postnatal depression?
60-70% have the baby blues (day 3-7)
10% have postnatal depression (starts around a month after birth)
What medication can be used to reduce uterine contractions in umbilical cord prolapse?
Terbutaline - a tocolytic drug
What is exomphalos?
When the abdominal contents of a foetus protrude through the anterior abdominal wall, but are covered in an amniotic sac
Which cancer does progesterone increase the risk of?
Breast cancer
Which cancer does unopposed oestrogen increase the risk of?
Endometrial cancer
Which antibiotic is used to treat group B strep in expectant mothers?
Benzylpenicillin
What is the management of pregnant women with new onset hypertension and pedal oedema?
Emergency admission to hospital to look for pre-eclampsia
What is the management of chicken pox in pregnancy?
Oral aciclovir if > 20 weeks
If exposure to varicella-zoster but no symptoms - give Iv Ig VZ asap
How is a diagnosis of PCOS made?
Rotterdam criteria - any two of
- oligomenorrhea, anovulation
- hyperandrogenism - clinical or biochemical signs
- polycystic ovaries on US scan
What condition should be suspected in an enlarged boggy uterus?
adenomyosis (endometrial tissue embedded in the myometrium)
When should you assess the APGAR scores in a baby?
1 and 5 mins of age
If it is low, repeat again at 10 mins
What investigations should be done for a suspected ovarian malignancy?
Seru CA-125, alpha fetoprotein, beta HCG, cystectomy
Where is beta HCG made?
It is first produced by the embryo and then the placental trophoblast. Secreted by the syncytiotrophoblasts, acts to prevent disintegration of the corpus luteum
What do you do for <24hr old baby with jaundice?
Measure serum bilirubin within 2 hours - under 24hrs it’s always pathological
What hypertension medication should be stopped in pregnancy?
ACE-I or ARB - change to labetalol
What is the most common cause of postmenopausal bleeding?
Vaginal atrophy
What is the guidance for the management of women over 55 with postmenopausal bleeding?
Should be investigated by transvaginal ultrasound within 2 weeks (suspected endometrial cancer)
What is a normal depth of endometrial lining thickness in post-menopausal women?
< 5mm