Part 2: PBI288 midterm Flashcards

1
Q

What is the all of nothing law (related to AP)

A

Once an AP is triggered it cannot be stopped.

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2
Q

What does an AP largely depend on

A

Movements of K+ and Na+

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3
Q

What does the neural tube come from

A

Neural grooves (once it closes)

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4
Q

What forms the neural grooves

A

The neural plates folds inwards creating the groove.

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5
Q

What is the most common birth defect called

A

Neural Tube defects

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6
Q

What does Neural Tube Defect lead to

A

Anencephaly and spina bifeda

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7
Q

How many structures are derived from the neural tube at 4 weeks of gestation

A

3

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8
Q

What are the 3 divisions of the neural tube at 4-weeks

A

1) Prosencephalon (forebrain)
2) Mesencephalon (midbrain)
3) Rhombencephalon (Hindbrain)

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9
Q

At week 7 of gestation, how many structures is there

A

1) Telencephalon
2) Diencephalon
3) Mesencephalon
4) Metencephalon
5) Myelencephalon

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10
Q

What are the 4 major steps of cellular behavior

A

1) Proliferation
2) Determination
3) Migration
4) Differentiation

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11
Q

What is proliferation

A

Increase the number of cells once that neural tube is complete.

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12
Q

What is determination

A

Cells will determine their destiny into becoming neurons or glial cells.

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13
Q

What is Migration

A

Neurons will proliferate and migrate to their final location

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14
Q

What is differentiation

A

Stem cells become specialized

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15
Q

What does the growth cone indicates

A

How axon develop

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16
Q

What ensures the axons survival

A

Trophic factors

17
Q

What are trophic factors secreted by

A

Target cells

18
Q

What are 3 neurodevelopmental abnormalities

A

1) Fetal Alcohol Syndrome
2) Autism Spectrum
3) Fragile X syndrome

19
Q

What is the fetal alcohol syndrome

A

Ingestion of alcohol week 3-4 week of embryo b/c it interferes with adhesion molecules.

20
Q
A