part 1

Question 1

What drugs are used for spasticity?

Answer 1

Baclofen

Dantrolene

Question 2

What drug is used for localized muscle spasm?

Answer 2

cyclobenzaprine 
Carisoprodol (Soma)

Question 3

-involuntary contraction of muscle or muscle group
-Causes:
epilepsy
hypocalcemia
pain syndromes: adult and chronic
trauma: localized skeletal muscle injury

Answer 3

muscle spasm

Question 4

Where are effects produced for these drugs for spasm and spasticity?

Answer 4

effects are produced through actions in the CNS

-except dantrolene

Question 5

What are some treatments for spasms?

Answer 5

• physical measures
• drug therapy
• analgesic anti-inflammatory (aspirin)

Question 6

What are the physical measures in the treatment of spasm?

Answer 6

• immobilization of affected muscle
• cold compresses
• whirlpool baths
• physical therapy

Question 7

• This medication is centrally acting (brainstem)
• reduces tonic motor activity
• most effective medication for its purpose
• may undergo significant enterohepatic recirculation
• caution use in liver impaired pt’s

Answer 7

Cyclobenzaprine (Flexeril, Fexmid)

-ineffective for pt’s with spasticity

Question 8

What are the AE’s of (Flexeril, Fexmid) Cyclobenzaprine and Carisoprodol (Soma)?

Answer 8

• CNS
• Anticholinergic
• Cardiac

Question 9

What medications are contraindicated with (Flexeril, Fexmid) Cyclobenzaprine and Carisoprodol (Soma)?

Answer 9

• antidepressants: MAOI’s

- alcohol and other CNS depressants

Question 10

What do we need to warn older adults about (Flexeril, Fexmid) Cyclobenzaprine and Carisoprodol (Soma)?

Answer 10

• increased fall risk

- sedation and cognitive impairments