Parkinsons Flashcards

1
Q

What are some motor symptoms in parkinsons

A

Hypokinesia
Bradykinesia
Rigidity
Rest
Tremor
Postural instability

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are some non motor symptoms of Parkinson’s

A

Dementia

Depression

Sleep disturbances

Bladder and bowel dysfunction

Speech and language changes

Swallowing issues

Weight loss

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the drug management of motor symptoms in Parkinsons

A

First line treatment if motor symptoms are decreasing quality of life - Levodopa (combined with carbidopa to make co-careldopa or benserazide to make co-beneldopa)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Managing non- motor symptoms: Daytime sleepiness

A

Modafinil

Don’t drive, inform DVLA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Managing non- motor symptoms: Nocturnal akinesia

A

First line: Levodopa or oral dopamine-receptor agonists

Second Line: Rotigotine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Managing non- motor symptoms: Postural hypotension

A

Midodrine

Fludrocortisone: second line

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Managing non- motor symptoms: Psychotic symptoms

A

Quetiapine

Clozapine as alternative

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Managing non- motor symptoms: Rapid eye movement

A

Clonazepam/ melatonin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Managing non- motor symptoms: Drooling of saliva

A

First line: Glycopyrronium bromide

Second line: Botulinum toxin Type A

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is given in advanced Parkinson’s disease

A

Apomorphine

(give domperidone to control nausea and vomiting associated with apomorphine)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Impulse control disorders are possible when patients are given what?

A

Dopaminergic therapy (levodopa, ropinorole, rotigotine)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are some com-t inhibitors

A

Opicapone
Tolcapone
Entacapone - changes colour to reddish-brown

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What colour can entacapone colour the urine

A

Red/brown

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Caution with bromocriptine

A

Pulmonary retropentoneal reactions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Caution with prampexole

A

Postural hypotension - give midodrine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is first line in Parkinsons Dementia

A

Rivastigmine