Depression

Question 1

How is chronic depression defined

Answer 1

More than 2 years

Question 2

After how long should antidepressant treatment be reviewed after starting

Answer 2

2-4 weeks

Question 3

When are benefits of antidepressant therapy seen

Answer 3

After 4 weeks

Question 4

How should you withdraw antidepressants

Answer 4

Gradually

Question 5

What is a good treatment in mild depression

Answer 5

Therapy, CBT

SSRIs (sertraline, fluoxetine, citalopram, escitalopram, paroxetine)

Question 6

Why should you not give St Johns wart with other medications

Answer 6

Major interactions with other drugs

Question 7

Which antidepressants have highest risk of overdose

Answer 7

TCAs

Question 8

Are TCAs effective in children

Answer 8

No

Question 9

When is vortioxetine offered?

Answer 9

When 2 antidepressants have not worked

Question 10

What is the risk with all antidepressants (electrolyte imbalance)

Answer 10

Hyponatremia

Question 11

What are the side effects of hyponatremia

Answer 11

Drowsiness, confusion, convulsions

Question 12

What are some symptoms of serotonin syndrome?

Answer 12

1. Neuromuscular hyperactivity (tremor, rigidity etc)
2. Autoimmune dysfunction (tachycardia, BP change, shivering)
3. Altered mental state ( agitation, confusion, mania)