Opioid substitution Flashcards

1
Q

What is used as subs therapy

A

Methadone and buprenorphine

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2
Q

How many days should not be missed otherwise risk of relapse

A

3 days

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3
Q

What is less sedating than methadone

A

Buprenorphine

But methadone is long lasting

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4
Q

Why should acute withdrawal of opioid therapy be avoided in pregnancy

A

Foetal death risk

Continue opioid therapy in pregnancy

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5
Q

What trimester should we withdraw methadone and buprenorphine in

A

Only in second trimester because if done in first trimester - risk of miscarriage and if done in third, can lead to stillbirth

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6
Q

Is methadone safe in breastfeeding

A

Lowest dose possible

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7
Q

When is methadone linctus indicated

A

Analgesia in severe pain and cough in terminal disease

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8
Q

What should be monitored on methadone linctus?

A

QT prolongation

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