Dementia Flashcards
1
Q
What is the most common type of dementia
A
Alzheimer’s disease
2
Q
What neurotransmitter is commonly associated with dementia
A
Acetylcholine - low levels of it
3
Q
What is the issue with drugs that have increased anticholinergic burden
A
Can worsen cognitive functions
Use should be minimised in dementia
4
Q
What drugs have high anticholinergic burden
A
Antidepressants: Amitriptyline, paroxetine
Antihistamines: chlorphenamine maleate, promethazine
Antipsychotics: Olanzapine, Quetiapine
Urinary antispasmodics: Solifenacin, tolterodine
Oxybutinin - urinary frequency - overactive bladder
5
Q
What drugs are used in dementia
A
Mild -moderate:
- Donepezil
- Galantamine
- Rivastigmine
Moderate-severe: Memantine
