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Neuro 2 > Parkinson's > Flashcards

Parkinson's Flashcards

8-10 questions

1
Q

Decreased levels of dopamine substania nigra → shift balance between acetylcholine (excitatory –high)

A

Parkinsonism

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2
Q

Tremors, Rigidity, Bradykinesia WITHOUT organic cause

A

Parkinson’s Disease

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3
Q

Parkinsonism:

A

Tremors, Rigidity, Bradykinesia w/ organic cause

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4
Q

Dopamine plays an important role in

A

posture, support and smooth movement

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5
Q

Parkinson’s Dx Requires

A

CARDINAL S/S FOR(2/3→ DX)

Tremor, rigidity, bradykinesia

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6
Q

Pill rolling tremor

A

rolling pill between fingers

Parkinson’s

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7
Q

Manifestations

A

Tremor, rigidity, bradykinesia
sustained muscle contraction (plastic- led pipe)
cog-wheeling (jerky stoping through ROM- Difficulty initiating movement (rocking to start)
masked facial expressions

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8
Q

Levidopa

A

converts to dopamine in the brain stem

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9
Q

Sinemet (Carbidopa + Levidopa)

A

wks to mo before effect seen
usually first prescribed,
best 1st few years, but effects fade
most improvement with bradykinesia

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10
Q

Apokyn

A

reverse s/s of immobility within 20 mins

severe n/v –>give w/ antiemetic

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11
Q

Side Effects of Apokyn

A

severe n/v –>give w/ antiemetic

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12
Q

Dyskinesia

seen w/ Sinemet Tx for Parkinson’s

A

(jerky/ riving movement) esp noticeable in face, mouth, tongue → Notify MD → Change med

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13
Q

Medications for the Tx of Parkinson’s

A 
Dopamine Agonist 
Anticholinergics
Antihistamines
Antivirals
MAO Inhibitors 
COM T Inhibitor
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14
Q

DO NOT give Parkinson Pts

A

Regland & Zofran

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15
Q

Medication timing for the Parkinson’s

A

must be meticulous → communicate what times the med are administer with pharm

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16
Q

Dopamine Agonist

A

Stimulate dopamine receptors)

17
Q

Anticholinergic in Parkinson’s

A

block activity of ACH to create a better balance

18
Q

Antihistamines in Parkinson’s

A

control tremors

19
Q

Antivirals in Parkinson’s

A

promote release of dopamine

20
Q

Monoamine Oxidase Inhibitors

MAOI’s

A

inhibit dopamine breakdown; Dangerous, lots of side effects

Neuro 2 (10 decks)

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