Guillain Barre Syndrome

Question 1

attack on the myelin of peripheral nerves characterized by ascending symmetrical muscle weakness

Answer 1

Guillain Barre Syndrome

Question 2

Onset, Gender

Answer 2

Rapid, Men, European- American, 50+

Question 3

Manifestations (Guillain Barre Syndrome)

Answer 3

Symmetrical Motor Weakness (Distal to Medial)
Parethesia & Pain (worse @ night)
Hypotonia/ Arreflexia
SIADH (Fluid Retention)

Question 4

Hx component of Dx (Guillain Barre Syndrome)

Answer 4

Prior respiratory/ GI Infection (30% Camplyobacter Jejuni)

Question 5

CSF (Guillain Barre Syndrome)

Answer 5

Protein normal to low initially, increases 7-10d

Question 6

EMG/ Nerve Conduction

Answer 6

Slows Transmission

Question 7

Tx (Guillain Barre Syndrome)

Answer 7

Plamaphoresis 
Immunoglobulin (Renal Function Important)

Question 8

NI’s (Guillain Barre Syndrome)

Answer 8

Ventilate before it becomes an emergency

suctioning, chest pain, intubation

Question 9

1 cause of mortality in pt with (Guillain Barre Syndrome)

Answer 9

respiratory failure

Question 10

Prognosis (Guillain Barre Syndrome)

Answer 10

Ventilator support for 2 weeks (typically)
ICU 2-3 months
Most pts survive, Extensive Rehab to recover (up to 2 yrs)