Inflammatory Conditions Flashcards
Most Inflammatory Conditions Originate
via blood stream
acute infection/ inflammation of meninges → inflammation of arachnoid and pia & infection CSF
Meningitis
Most Common Types of Meningitis
Viral/ Bacterial
Meningitis is usually associated with
upper respiratory infection
smokers, dorms, imun deficient, chronic disease, elderly
purulent secretions- spread to brain via csf→ cell death, cerebrall edema & increased intracranial pressure (IICP)
Bacterial Meningitis
80% of all Bacterial Meningitis cases are caused by….
streptococcus pneumonia and neisseria meningitides
The least cases of Bacterial Meningitis occur …
The only safe season is…
in the summer (summer is the safest)
The 1st s/s of Bacterial Meningitis
Severe Progressive HA
Other s/s include: Fever, N/V, skin rash and petechial (meningeal cocyl)
Classic Signs of Bacterial Meningitis
Nuchal Rigidity
+Brudzinski Sign (B for Bend)
+Kernig (K for kinked legs)
–>(d/t meninge irritation)
Nuchal Rigidity
early sign→ neck stiff & painful with neck flexion
Positive Brudzinski’s Sign
examiner flexes patient’s neck & knees flex
Positive Kernig
laying down, hip flexed, cannot extend knee
Complications of Bacterial Meningitis
IICP (Increased intracranial pressure)
DIC-disseminated intravascular coagulation
Shock
IICP (Increased intracranial pressure) with Cranial nerve (CN 2) involvement
optic nerve: photophobia (very common) blindness, hemianopsia
hemianopsia
decreased vision or blindness in half the visual field of one or both eyes, usually on one side of the vertical midline
IICP with Cranial nerves (CN 3,4,6) involvement
ptosis, diplopia
Eyelid drooping is excess sagging of the upper eylid
ptosis
diplopia
double vision
IICP with Cranial nerve (CN 8 ) involvement
acoustic nerve: tinnitus, vertigo, deaf (may be permanent)
IICP with Cranial nerve (CN 3 ) involvement
occulomotor: pupils dilated/ sluggish
DIC
countless small clots formation→ slowed blood flow→ **depleted platelets → risk for bleeding **
Waterhouse-Friderichsen syndrome
severe vascular dysfunction (shock)
Dexamethasone
reduces mortality and hearing loss; decreases/ combats cerebral edema in bacterial meningitis
acyclovir
Antiviral for Encephalitis
HSV Viral encephalitis)
localized collections of pus within the brain tissue
Brain Abscess
Temporal Lobe Encephalitis –>
visual field deficits, receptive aphasia
Occipital Lobe Encephalitis
visual impairment
Frontal Lobe Encephalitis
expressive aphasia, motor weakness
Cerebellar Encephalitis
ataxia