Huntington's Disease

Question 1

Chorea

Answer 1

Jerky, brisk, and purposeless movements asc. w/ HD

Question 2

deficiency in the neurotransmitters gaba & acetycholine→

Answer 2

too much dopamine

PATHO asc w/ HD

Question 3

an affected parent has a ________of having a child with HD

Answer 3

50%

Question 4

HD Gene

Answer 4

IT 15

Question 5

Disease Characteristics (HD)

Answer 5

chronic, progressive, no cure, (rare=30,000)

M=F

Question 6

Onset

Answer 6

Gradual

30-50 yo

Question 7

o Disease of the nervous system that results in involuntary choreiform movements and mental status changes→ riving and twisting movement

Answer 7

Huntington’s Disease

Question 8

riving and twisting movement

Answer 8

Huntington’s Disease

Question 9

Xenazine (tetrabenazine)

Answer 9

decreases available dopamine

Question 10

Neuroleptics

Answer 10

Haldol, Valium, Klonopin, Risperdal (bipolar med)

Question 11

Meds that treat Cognitive and Psychiatric symptoms of HD

Answer 11

Zoloft, Risperdal

Question 12

Calories per day for HD

Answer 12

4000-5000 calories per day to maintain

Question 13

Prognosis

Answer 13

Death 10-20 years after onset

Question 14

Xenazine (tetrabenazine)

Answer 14

treats chorea by decreasing available dopamine

Question 15

Neuroleptics

Answer 15

Haldol, Valium, Klonopin, Risperdal (antipsychotics) For HD

Question 16

Zoloft, Risperdal (bipolar med)

Answer 16

Treat HD