Parkinson's Flashcards
classic manifestations of parkinson’s
TRAP - tremors, rigidity, akinesia, postural instability
other manifestations of Parkinson’s
slow, quiet, slurred speech; incontinence or dysuria, constipation
how do tremors start
minimal resting tremors, first noticed by patient, starts in upper extremities
what can aggravate tremors
stress
how does rigidity progress
cogwheel, plastic, lead pipe
cogwheel rigidity
jerky, stop and go movement
plastic vs lead pipe
plastic - mildly resistant
lead pipe - total resistance to movement
facial appearance
mask-like; wide, fixed, staring eyes with excessive drooling
akinesia
loss of control of voluntary muscle movements and “automatic” movements
Parkinson’s gait
shuffling, cannot stop themselves from going forward/backward
Parkinson’s dx
no specific test - confirmed by positive response to antiparkinsonian drugs
primary med for Parkinson’s
Levodopa Carbidopa
side effects of levodopa carbidopa
n/v, dry mouth
foods with tyramine
soy sauce, tuna, red wine, beer, smoked food, sausage
examples of dopamine receptor agonists
ropinirole, pramipexole, rotigotine