Parathyroid Pathology Flashcards

1
Q

what are the lobes of the parathyroid

A

right and left superior and inferior

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2
Q

what do the superior lobes of the parathyroid develop from?

A

fourth pharyngeal pouc

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3
Q

what do the inferior lobes of the parathyroid develop from?

A

third pharyngeal pouch

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4
Q

mixed in with chief and oxyphil cells in the parathyroid is what?

A

25% adipose tissue

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5
Q

what is parathyroid hyperplasia?

A

two or more glands are enlarged and have an increase in epithelial cells

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6
Q

what do you not see much of in parathyroid hyperplasia?

A

fat in the gland

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7
Q

what is main symptom of parathyroid hyperplasia?

A

increased serum calcium

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8
Q

do you see any normal parathyroid tissue in hyperplasi?

A

no

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9
Q

what happens in parathyroid adenoma?

A

benign neoplasm of the parathyroid

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10
Q

what is seen on histo with paratyroid adenoma?

A

compressed rim of normal parathyroid tissue with one enlarged gland

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11
Q

what are symptoms of parathyroid adenoma?

A

usually just elevated serum calcium

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12
Q

what happens in parathyroid carcinoma?

A

malignant neoplasm of parathyroid

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13
Q

what are the three types of invasion that occur in parathyroid carcinoma?

A

capsular
vascular
metastatic

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14
Q

what happens in osteitis fibrosa cystica?

A

loss of bone mass as calcified supporting structures become fibrous tissue

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15
Q

what disease leads to osteitis fibrosa cystica?

A

hyperparathyroid

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16
Q

what bone imaging thing can you see with osteitis fibrosa cystica?

A

browns tumor

17
Q

what four things occur in bone in osteitis fibrosa cystica?

A

increased osteoclast activity
hemorrhage
cyst formation
fibrosis