Parasite 6: Nematodes 5 Flashcards
Order Spirurida is described as?
Very long and thin
-confused with ascrid
What do all members of Spirurida have?
have an arthropod as intermediate host
Are Spirurida usually in the GIT?
NO not usually
What is the super family Filaroidea of Spirurida located?
What do Spirurida Filaroida a larvae (oviviparous) called?
Pre L1 = microfilariae
Dirofilaria immitis (Heart worm) is what kind of
host?
where is it located?
shape/length?
Definitive host = DOGS
Parasite of pulmonary arteries primarily (not IN HEART)
Long, thin; females up to 28cm in length
What is the life cycle of Dirofilaria immitis (Heart worm)?
Mosquito feeds and ingests microfilariae with blood
microfilaria matures in mosquito to infective L3 larva, 2 weeks post infection
infective larvae deposited during subsequent bites migrate through wound and into host
What is the PPP of Dirofilaria immitis (Heart worm)?
6 months
How long is the patency of Dirofilaria immitis (Heart worm)?
5 years
What is the pathogenesis of Dirofilaria immitis (Heart worm)?
Damage roughly proportional to worm numbers
* Probably no clinical signs with lower numbers
Disease components
* Some physical obstruction of vessel by worms
* Worms cause inflammation in vessel wall
* Progressive fibrosis in vessel (sclerosis)
Reduced cardiac output and compensatory right heart disease with severe disease
* Right heart enlargement and failure
Potential thromboembolism
Clinical signs of Dirofilaria immitis (heart worm)?
Chronic cough
Dyspnea
Decreased excercise tolerence
Where is the Prevalence of Dirofilaria immitis?
Highest:
along the MISSISSIPPI
and east coast
What is the best way to diagnosis Dirofilaria immitis?
Annual test recommended
Antigen tests: most sensitive and widely used
Microfilaria check
–> check peripheral blood sample for MF
Covered in detail in breathing and circulating
What is the treatment for Dirofilaria immitis?
PREVENTATIVES
Treatment is harsh and accompanied by risk of thromboembolism
What role of WOLBACHIA in Dirofilaria immitis?
Many, but not all filarid parasites have symbiotic bacteria,
Wolbachia
*If bacteria is removed, the reproduction of the worms is blocked, reduces severity of disease
*Doxycycline now being used in treatment of heartworm infections
What is the abnormal host of Dirofilaria immitis?
Cats
-more likely to migrate to abnormal sites than in dogs
-NOT showing sign
-worms die soon after infections
Other Filaroidea in North America?
Not common!
subQ tissue in dogs
dermatitis in horses
good indication when parasite NOT in GIT and microfilariae detected
Habronema and Draschia spp.
- Live in nodules in equine stomach
- IH: Stable and house fly
- L3 can be deposited by mistake in other locations
-Mucocutaneous junction
-Wounds
-Larvae invade areas and survive but don’t develop - Causes “summer sore”
-Persistent cutaneous granuloma
-Can be mistaken for exuberant granulation tissue, neoplasia
Non-Filaroidea examples are
Physaloptera
- Stomach parasite of wild animals, occasionally in dogs and
cats
Thelazia
- Eye worm - Zoonotic
The order Enoplida is part of phylum nematoda and it’s described as?
Without many common characteristics
*Most in domestic animals produce eggs with 2 polar plugs
*Infective larva develops and remains inside the egg
*Eggs very resistant to environmental conditions
Trichuris vulpis - Whipworm
- Large intestine of dogs, worldwide
- Whip shaped body
- Anterior end entwined within layer of epithelial cells
- Direct life cycle**
- Bipolar eggs passed in feces
- Infective larva develops in eggs (at lest 2 weeks):
- EMBRYONATED EGG IS THE INFECTIVE STAGE
- Diagnosis:
- egg detection
*Clinical disease:
- Diarrhea with/without blood (anemia)
-can be asymptomatic
What is the PPP of Trichuris vulpis is?
3 months
this does NOT effect young animals mostly adults
Are Tichuriss spp. can effect other animal?
Pigs
Ruminants
NOT cats – only FL and other countries
people their own species
Trichinella spp- Human disease: Trichinellosis or Trichinosis
Order Oxyurida big identifiers?
PINWORMS
- Usually small adults in large intestine
- Species in horses, rodents, ruminants, reptiles, people
- Usually NOT very pathogenic
- Direct life cycle
- Egg may have polar plug, often flattened appearance on one side
- Diagnosis by detection of eggs in feces of perianal swabs
Oxyuris equi
- Common equine pinworm
- Life cycle
-Infection from ingestion of eggs
-Fertilized females migrate from LI and rectum onto skin, glue eggs to hairs in perianal area - Causes pruritus, irritation from worm movement and egg glue
- “Rat tailed” appearance
- Diagnosis by finding eggs on perianal skin
Rhabditida
- Most members are free living soil nematodes
- Only one animal parasite genus: Strongyloides
- Tiny adults (about 6 mm) in SI
- Species specific for ruminants, horse, dog, pig, human
- Strongyloides eggs common in manure samples from young ruminants, rare to see disease
What are host and the species name of order Rhabitida?