PAPER 2 - BIOPSYCHOLOGY - functional recovery of the brain Flashcards
what is functional recovery?
the ability to recover abilities and mental processes that have been compromised or lost due to brain injury or disease
how is functional recovery achieved?
achieved as a result of neural regeneration and neural reorganisation/rewiring
what kinds of brain trauma can result in loss of function?
- physical trauma
- viral or bacterial infections
- stroke
- cerebral haemorrhage
what are the mechanisms for functional recovery?
- neural regeneration
- neural reorganisation
what is neural regeneration?
regrowth or repair of nervous tissues, cells or cell products
what does neural regeneration include?
- axonal sprouting
- generation of new neurones (neurogenesis), axons, myelin
what is neural reorganisation?
- transfer of functions to undamaged areas to allow functional recovery
- axonal sprouting allows reorganisation to happen
what can neural reorganisation take place as a result of?
- synapse strengthening
- axonal sprouting
- neuronal unmasking
what is axonal sprouting?
axons of surviving neurones grow new branches that make new synapses
what is synapse strengthening?
damage to one brain region can result in synapses in nearby regions to become strengthened to allow these neurones to take on the functions of damaged brain region
what is neuronal unmasking?
dormant synapses become unmasked if sufficiently stimulated
what factors can influence recovery?
- age
- cognitive reserve
what was the study by Teuber?
- Teuber studied soldiers with brain damage and found that recovery from movement and visual problems in adulthood was age dependent
- 60% of those under 20 showed significant improvement, but only 20% over 26 showed similar recovery
- therefore suggested that axonal sprouting and reorganisation may be extensive in younger brains
what are the evaluation points for the Teuber study?
- shows brain plasticity can take but it is affected by age
- could be individual differences - brain damage may vary
- lots of research support
- cant establish cause and effect
- age range isn’t comparable (18-20 vs 26+)
- p’s could have multiple injuries
- stress hinders recovery
what was the study by Schneider? (procedure and findings)
- found that patients with the equivalent of a college education are 7x more likely than those who didnt finish high school to be disability-free one year after a traumatic brain injury
- carried out a retrospective study based on previous data
- of the 769 patients, 214 achieved disability free recovery
- of these 39.2% patients with more than 16 years of education achieved DFR, as had 30.7% with 13-15 years of education
- 9.7% achieved DFR with less than 12 years of education
- shows cognitive reserve could be a factor affecting recovery