Pancreatic Carcinoma Flashcards
1
Q
Pancreatic Carcinoma Epidemiology
A
- Most exocrine, 90% of these are adenocarcinomas
- Peak incidence at 70-80
2
Q
Pancreatic Carcinoma RFs
A
- Smoking diet, diabetes, alcohol
- Chronic pancreatitis
- FHx of pancreatic CA
3
Q
Pancreatic Carcinoma Presentation
A
- Vague and nonspecific
- Epigastric discomfort, dull back ache
- Painless, progressive, obstructive jaundice
- Tumours in body and tail much less likely to cause obstruction
- Presentation may be due to paraneoplastic diseases e.g. thromboembolic
- Pancreatitis may be presentation
- WL, anorexia
- Steatorrhoea, mass
- Corvoisier’s sign
4
Q
Pancreatic Carcinoma Differentials
A
- Gallstones
- Peptic ulceration
- Gastric cancer
- Oesophagitis
- Hepatitis
5
Q
Pancreatic Carcinoma Ix
A
- Bloods
- Glucose: hyperglycaemia
- Tumour markers
- USS
- CT
- Endoscopic USS
6
Q
Pancreatic Carcinoma Management
A
- Surgical resection offers cure however only 10-20% are resectable
- Unresectable disease
- Palliative
- Coeliac plexus block may help to control pain which can be severe and resistant
