Pancreas and Adrenals Flashcards

1
Q

What are the 2 portions of the adrenal glands and what do they secrete?

A
  1. Cortex: Aldosterone, Cortisol

2. Medulla: Epinephrine and Norepinephrine.

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2
Q

What are the zones of the cortex from outer to inner most layer and what do they produce?

A
  1. Zona Glomerulosa: Mineralocorticoids
  2. Zona Fasciculata: Glucocorticoids
  3. Zona Reticularis: Endocrine cells that produce androgens
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3
Q

What does aldosterone do?

A

Stimulates conservataion of sodium and elimination of potassium. Helps raise blood pressure.

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4
Q

What disorders happen during hypo and hyper secretion of glucocorticoids?

A
  1. Hypo: Addison disease

2. Hyper: Cushings syndrome

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5
Q

what kind of exocrine cells are in the pancreas and what do they secret?

A

Pancreatic acini, secrete alkaline, enzyme rich fluid.

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6
Q

What are the endocrine cells of the pancreas and what do they secrete?

A
  1. Alpha cells: Glucagon
  2. Beta cells: Insulin
  3. Delta cells: GH-IH peptide hormone.
  4. F cells: Pancreatic polypeptide PP
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7
Q

What is diabetes mellitus?

A

High Glucose concentrations overwhelmm reabsorption capabilities of kidneys.

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8
Q

What is type I and II diabetes mellitus?

A

I=Insulin dependent

II=Insulin independent

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9
Q

What does GH do in children and adults?

A
  1. Child: Supports muscular/skeletal growth.

2. Adult: Maintains blood glucose, mobilizes lipid.

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10
Q

What happens when Thyroid hormones During fetal development? Decline before puberty?

A
  1. Fetal: Nervous system fails to develop.

2. Normal skeletal dev will not continue.

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11
Q

What happens if PTH and Calcitrol are inadequate?

A

Causes weak and flexible bones, as they promote deposition of Ca in bones.

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12
Q

What is General Adaptation syndrome? What are the phases?

A

Stress response.

  1. Alarm (Fight/flight)
  2. Resistance
  3. Exhaustion
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