Pancreas Flashcards
Is the pancreas encapsulated?
NO
Where does the pancreas lie in the abdomen?
Retroperitoneal
Between the duodenal loop and the splenic hilum
What are the different parts of the pancreas?
Head, uncinate process, neck, body, and tail
What is the exocrine function of the pancreas?
Secrete trypsin, lipase and amylase
What is the endocrine function of the pancreas?
Secrete insulin via islets of Langerhans
What is the normal size of the pancreas in AP dimension?
<3 cm
What overlies the anterior border of the pancreatic body and tail?
Posterior wall of the stomach
Where is the head of the pancreas?
Anterior to the IVC and medial to the duodenum
Where is the CBD in relation to the pancreas?
Posterior and lateral to the pancreatic head
Where is the gastroduodenal artery in relation to the pancreas?
Anterior and lateral to the pancreatic head
Where is the SMA/V in relation to the pancreas?
Posterior to the neck of the pancreas and anterior to the uncinate process
Where is the pancreatic tail located?
Anterior and medial to splenic hilum
Where does the aorta lie in relation to the pancreas?
Posterior to the body of the pancreas
What does the celiac axis divide into?
Left gastric artery then divides into the common hepatic artery and splenic artery
What does the common hepatic artery divide into?
Proper hepatic and gastroduodenal arteries
Where does the proper hepatic artery travel towards?
Travels superiorly toward the liver, anterior to the portal vein, and left of the bile duct
Where does the right gastric artery come from?
Proper hepatic artery
Where does the gastroduodenal artery travel?
Posterior to the first portion of the duodenum then anterior to head of pancreas
What does the GDA divide into?
Right gastroepiploic artery
Superior pancreaticoduodenal artery
Where is the SMA located?
Inferior to pancreas
Anterior to uncinate process
Anterior to 3rd portion of the duodenum
Where is the splenic vein located?
Posterior aspect of the pancreas
What 2 veins make up the main portal vein?
Superior mesenteric vein and splenic vein
Where is the SMV located?
Right of the SMA
Anterior to the 3rd portion of the duodenum
Anterior to uncinate process
What does the IMV drain?
Left lower quadrant sigmoid and descending colon into the splenic vein
Where does the CBD travel?
Posterior to 1st portion of the duodenum and head of pancreas
Right of main pancreatic duct
Where does the ampulla of Vater open into?
2nd portion of duodenum at major papilla
Where does the accessory pancreatic duct (duct of Santorini) open into?
2nd portion of duodenum at minor papilla
How many portions does the duodenum divide into?
4
1st and 3rd - transverse
2nd and 4th - longitudinal
At what size is the pancreatic duct considered abnormal?
> 2.0 mm
What structures are in contact with the pancreatic head?
IVC CBD Ampulla of Vater Gastroduodenal artery Duodenal C loop (2nd portion)
What are the most common causes of acute pancreatitis?
Gallstones
Alcohol abuse
What are sonographic findings of acute pancreatitis?
Enlarged hypoechoic gland
What are some complications of acute pancreatitis?
Pseudocyst formation Abscess Pancreatic necrosis Hemorrhage Venous hemorrhage Pseudoaneurysm formation
What is a pancreatic phlegmon?
Focal pancreatitis
Inflammatory mass formed by edema and leakage of pancreatic enzymes
What are causes of chronic pancreatitis?
Alcoholic chronic pancreatitis Autoimmune Hereditary CF Congenital abnormalities Abdominal trauma Idiopathic
What are sonographic findings of chronic pancreatitis?
Small and echogenic gland Calcifications Pancreatic duct dilatation Bile duct dilatation Portal vein thrombosis
What diseases are multiple pancreatic cysts associated with?
Adult PCKD
Von Hippel-Lindau syndrome
What are US findings of CF of the pancreas?
Increase pancreatic echogenicity
Gland atrophy
Fibrosis and fatty replacement
Cysts due to ductal obstruction
What condition is associated with CF?
Meconium ileus
What are pancreatic pseudocysts?
Accumulation of pancreatic fluid and necrotic debris confined by the retroperitoneum
What causes pancreatic pseudocysts?
Acute pancreatitis Chronic pancreatitis Pancreatic trauma Pancreatic ductal obstruction Pancreatic neoplasms
Where in the retroperitoneum is the pancreas located?
Anterior pararenal space
What is the most common cause of a pancreatic pseudocyst in children?
Trauma
What is a pancreas divisum?
Failure of the dorsal and ventral pancreatic ductal systems to fuse during embryonic development which results in the smaller Santorini’s duct draining the pancreas
What is an annular pancreas?
Congenital anomaly where the ventral pancreas encircles the second portion of the duodenum
What may present as a “double-bubble” sign?
Annular pancreas - dilated stomach and duodenal bulb
How do pts with pancreatic CA present?
Lymphatic and metastatic spread of tumor
Mean pt age 55yo
80% arise from pancreatic head
What are sonographic findings of pancreatic adenoCA?
Solid hypoechoic mass
What are associated findings of pancreatic adenoCA?
Courvoisier's GB Bile duct dilatation Dilated pancreatic duct Liver mets Ascites Lymphadenopathy Pseudocyst formation
What is the Whipple procedure?
Pancreaticoduodenectomy
Head of pancreas, portion of bile duct, the GB and duodenum are removed
Are pancreatic serous cysteadenomas malignant?
NO
Formerly microcystic cystadenomas
What do pancreatic serous cystadenomas look like on US?
Cluster of grape-like cysts
External lobulation
What do mucinous cystic neoplasms look like on US?
Large multicystic mass with numerous septations and debris
What is increased in mucinous cystic neoplasm?
CEA levels
What are islet cell tumors associated with?
MEN-1
Von Hippel-Lindau disease
What are the islet cell tumors?
Insulinoma - most common Gastrinoma - Zollinger-Ellison Syndrome Glucagonoma Vipoma Somatostinoma
What is Multiple Endocrine Neoplasia?
Inherited endocrine disorder
MEN type 1 - Wermer’s syndrome
MEN type 2 - Sipple’s syndrome
What organs does MEN affect?
Parathyroids Pancreatic islet cells Pituitary glands Adrenal glands Thyroid
Where does amylase come from?
Digestive enzyme for carbs, produced by pancreas and salivary glands; also kidneys
Head of pancreas is anterior to?
IVC
Head of pancreas is medial to?
2nd portion of duodenum
CBD is posterolateral to?
Head of pancreas
GDA is anterolateral to?
Head of pancreas
SMA and SMV are posterior to?
Neck of pancreas
Uncinate process is posterior to?
SMA and SMV
Aorta is posterior to?
Body of pancreas
Celiac axis is superior to?
Pancreas
Splenic vein is posteroinferior to?
Pancras
SMA and SMV are anterior to?
3rd portion of the duodenum
SMV is to the right of?
SMA
Stomach is anteromedial to?
Splenic hilum
Stomach is anterior to?
Pancreas body and tail
Tail of pancreas is posterior to?
Stomach
Tail of pancreas is anterior to?
Upper pole of left kidney
Splenic artery is superior/anterior to?
Pancreas