Pallor and Jaundice Flashcards
Biliverdin in birds
Liver disease resulting in failure of excretion of biliverdin via the bile usually
results in excretion via the kidney resulting in green colouration of the urates
–
biliverdinuria.
Clinical signs of liver disease
How do you diagnose liver disease in birds?
Serum/plasma chemistry and Radiology (large or small– normally hour-glass shadow of the liver)
** Increases in AST and/or LDH (while CK remains steady) and/or bile acids stronly suggests liver disease
Other signs of liver disease
Problems with serum chemistry and the diagnosis of liver disease
Normal liver
Diagnostic approach to liver disease
Diagnostic approach for necropsy cases
* Impression smear–> Gram/Giemsa stain
* Swab or fresh tissue–> Microbiology or PCR
* Fixed tissue–> histopathology
Mycotoxicosis… most commonly– Aflatoxicosis
Diseases of the avian liver
Bacterial hepatitis- common causes?
Inclusion body hepatitis
Young chickens (broilers)
2-6 weeks old
Adenovirus (one of 12)
Acutely swollen liver with multiple pale and/or haemorrhagic foci
Confirmed by histopath
Outbreaks in AUS caused by pathogenic viruses without previous immunocompromise
No treatment– there is a vaccine (live or killed)– minimal cross protection between 12 adenoviruses)