Pain PPT McDizzels Flashcards
Josh's guide to McDizzles riveting lecture on pain!!!!!!!! drop your socks grab your cocks you in for a ride!!!!!!!!!!
Fun Fact
Benedictus de Spinoza stated “pain is a localized form of ________”
sorrow
3 psychosocial factors that influence pain?
- intRApersonal (occurs within self)
- intERpersonal (Occurs between individuals)
- Social
where does pain Happen?
“brain”
pain isn’t pain until it gets to the brain
With the gate theory what happens when the gate is open?
pain
With the gate theory what happens when the gate is closed?
no pain
In relation to the DH (dorsal horn) NT (neurotransmitters):
what is found in large calls?
Excitatory amino acids (glutamate and aspartate)
In relation to the DH (dorsal horn) NT (neurotransmitters):
What do small cells contain?
- FRAP (fluoride-resistant acid phosphatase
- sP
- VIP (Vasoactive intestinal polypeptide)
- Somatistatin
- CCK (cholecystokinin)
- GRP (gastrin-releasing peptide
- CGRP (calcitonin-gene-related peptide
- ENK (leuenkephalin)
- DYN (dynorphin)
What are the 3 primary pathways to the brain? (ascending tract)
- Spinothalamic tract (STT)
- Spinoreticular tract (SRT)
- Spinomesencephalic tract (SMT)
Acute pain is a __________ experience!
multdimensional
Somatic events of acute pain are termed in:
- space, time, intensity
- motivational-emotional mechanisms
- Aversive behavior (avoiding behavior)
Psychological components or acute pain are?
- sensory-discriminative
- motivational-affective
- cognitive-evaluative
Visceral Structures (pain): what type of fibers involved
C-afferent fibers
A-delta fibers
(visCerAl)
Visceral Structures (pain): when do the C-afferent and A-delta fibers get activated? (what causes this type of pain)
-disease
-inflammation
-isometric contraction
-ischemia
-rapid distention
(remember these are organs- thus when you get appendicitis you hurt from the inflammation stretching, ischemia etc)
Visceral Structures (pain): C-afferent and A-delta fibers are activated by what?
noxious stimuli
alogenic substances
Visceral Structures (pain): the C-afferent fibers and A-delta fibers act as what???/
transducers
Visceral Structures (pain): the C-fibers and A-delta fibers are conducted to the \_\_\_\_ \_\_\_\_\_\_ or \_\_\_\_\_\_\_\_
dorsal horn
or
medulla
Visceral Structures (pain): The C-fibers and A-delta fibers are conducted to the dorsal horn and medulla, and are influenced by what?
intensity
duration
microenviroment
What are 2 ways to decrease pain?
- augmentation
- inhibition
what is inhibition
- counterirritation
- -rubbing, vibration, more sophisticated methods
what is augmentation?
- sensation by repeated noxious stimuli
- lowering the threshold by alogenic substances
What opens the Gate after nerve injury?
decreased inhibition
increased excitation
what the reduction in inhibitory postsynaptic currents the consequence of (r/t peripheral nerve injury related pain)
decreased GABA responsiveness