Pain pharmacology Flashcards
1
Q
What is a nociceptor?
A
Pain receptor found in all organs except brain
2
Q
What is a Type A nocioceptor?
A
Myelinated pain receptor (fast, sharp & localized)
3
Q
What is a Type C nocioceptor?
A
Unmylenated pain receptor (slow dull & unlocalised)
4
Q
What causes somatic pain?
A
Skin & deep tissue responding to cuts, muscular stretches & fractures
5
Q
What causes visceral pain?
A
Ischemia & inflammation
6
Q
How do endogenous opioids work?
A
Prevent release of excitatory neurotransmitters at spinal cord, midbrain, thalamus & cortex