Pain Pathways And Control Flashcards
Name the stages of pain perception and which are ascending or descending pathways
Transduction - A
Conduction -A
Transmission -A
Modulation -A
Perception -D
How can pain perception be altered
Subjective experience may influence pain interpretation
Adrenalin
What are pain receptors
Noiciceptors
What does a B1/B2 receptor detect
Bradykinin (. Peptide that causes vasoconstriction for inflammatory response)
Describe Transduction
Ion channels in the cell membrane open
Depolarise the membrane
Trigger an action potential that gets propagated
What os the passage of an action potential in conduction
From receptor to dorsal horn of spinal cord tract
What is pain transmission
Transmission of signals along a Sensory pathway in spinal cord that ascends to brain
What is a first order neuron
Neurons between periphery (outer regions) to spinal cord
Where a second order neurons
Between spinal cord and thalamus
Where are third order neurons
Between thalamus to sensory cortex
What is the spinocervicothalamic pathway
A transmission pathway in carnivores for rapid transmission of signals from skin to cerebral cortex
Registered touch
What is the spinoreticular pathway
Fibres ascending through contralateral cord
Reaches the brainstem before the thalamus, then the cortex
Activates limbic system (emotion)
Also visceral pain is detected
Which fibres conduct signals more slowly and why
C fibres
Have the smallest diameter
What fibres respond to only mechanical and thermal stimuli
Alpha gamma
Which fibres are unmyleinated
C fibres
