Neurological Cytology Flashcards
What are the function of dendrites
Receives signals from other neutrons
What is the function of the axon
Transmit electrical impulses to pre synaptic terminals
What is the function of Oligodendrocytes (Schwann cells in the PCN)
Form the myelinated sheath
Give nutrients to neuron
How do oligodendrocytes make the myelin sheath
The phospholipid membrane wraps around the axon,
This creates a fatty layers that prevents signals from passing through
What is the function of Astrocytes
Structural support of neuron
What is the function of Microglia
Cellular clearance after injury
Describe how the signal gets transmitted across the synapse**
Action potential sent down the axon
Cause Ca2+ ion channels to open, causing an influx of calcium into the cell
Triggers the release of neurotransmitters from the vesicles to the synaptic cleft
Neurotransmitters diffuse over the synapse
Bind to post synaptic receptors
How to excitatory neutrons change the resting potential
Add a more positive charge
Describe action potential generation***
- A stimulus distrusts the membrane, cause Sodium to enter the cell (stretch mediated)
- Resting potential meets threshold - opens Voltage Gated sodium channels, cause an influx in Na+ ions - depolarises the membrane.
- eventually K+ ion channels open, so K+ leaves the cell - repolarises the membrane
- K+ ion channels are slow closing so the cell will reach hyperpolarisation (voltage falls below resting potential)
- Na+ K+ pump brings membrane back to resting potential
How is there a net negative resting potential
Sodium potassium pump, pumps more sodium out the cell than potassium in
Why is action potential propergation unidirectional
Potassium channels are opened after AP is generated, so AP cannot be triggered as Voltage gated Na+ channels are closed (can’t be opened as cell has incorrect voltage)
What is the refractory period
Time where a new action potential cannot be produced in the cell
What is temporal summation
Frequency of action potentials increase to increase the intensity of the stimulus
What is spatial summation
Multiple neutrons secrete neurotransmitters to o me post synaptic membrane