Pain Meds

Question 1

Tramadol Drug Class

Answer 1

synthetic opioid analgesic

Question 2

Tramadol Indication

Answer 2

moderate/severe pain

Question 3

Tramadol SE

Answer 3

1. dizziness
2. flushing
3. pruritis
4. seizures
5. constipation

Question 4

Tramadol contra/dx-dx

Answer 4

1. MAOIs

2. SSRI

Question 5

Acetaminophen Class

Answer 5

analgesic-antipyretic

Question 6

Acetaminophen MOA

Answer 6

• CNS anti-prostaglandin

- blocks peripheral pain impulse

Question 7

Acetaminophen Indications

Answer 7

mild/moderate pain, fever

Question 8

Acetaminophen SE

Answer 8

1. increased ammonia
2. blood dyscarasias
3. edema, rash

Question 9

Acetaminophen dx-dx

Answer 9

1. anti-convulsants lower APAP

2. increase warfarin

Question 10

Acetaminophen monitor

Answer 10

liver

Question 11

Ibuprofen class

Answer 11

Traditional NSAID

Question 12

Ibuprofen MOI

Answer 12

1. inhibit COX1 and COX2 enzymes

2. reduces PG, prostacyclin, thromboxane

Question 13

Ibuprofen Indication

Answer 13

pain due to inflammation

Question 14

Ibuprofen contra

Answer 14

1. HTN
2. CKD
3. HF
4. CVD
5. h/o GI bleed

Question 15

Ibuprofen dx-dx

Answer 15

1. anticoags
2. diuretics
3. lithium

Question 16

Ibuprofen other

Answer 16

1. gastric protection with PPI
2. problems with ASA
3. salt-retaining (causes fluid retention)

Question 17

Celebrex drug class

Answer 17

Cox2 selective NSAID

Question 18

Celebrex MOA

Answer 18

Inhibits COX2 (reduces PG, prostacyclin)

Question 19

Celebrex Indications

Answer 19

pain secondary to inflammation

Question 20

Celebrex SE

Answer 20

LOTS!

increased clotting

Question 21

Celebrex Contraindications

Answer 21

1. HTN
2. CKD
3. HF
4. CVD

Question 22

Celebrex dx-dx

Answer 22

1. other NSAIDS
2. diuretics
3. lithium
4. anti-htn

Question 23

Celebrex other

Answer 23

helps elderly with GI bleed but increases CVD problems

Question 24

Cox 1 Enzyme

Answer 24

1. Constituative
2. gastric mucosa, kidney, platelets
3. Prostaglandins (protect gastric mucosa, dilate afferent artery glomerus)
4. Thromboxanes (vasocontriction, platelet aggregation)

Question 25

Cox2 Enzyme

Answer 25

1. Inducible
2. most tissues
3. prostaglandins (pain, fever)
4. prostacyclins (vasodilation, anti-platelet activity)

Question 26

Prednisone class

Answer 26

glucocorticoids

Question 27

Prednisone MOA

Answer 27

Inhibition of cytokines and inflammatory mediators

Question 28

Prednisone Indication

Answer 28

short-term RA use

Question 29

Prednisone SE

Answer 29

1. weight gain
2. decreased wound healing
3. osteoporosis
4. HTN
5. mood
6. cataracts
7. dyslipidemia

Question 30

Prednisone Contra

Answer 30

infection, TB

Question 31

Prednisone dx-dx

Answer 31

Lots!

TB

Question 32

Prednisone other

Answer 32

down titrate dosing if more than 2 weeks

PG: C/D