Pain Flashcards
what are the 4 main pain pathways
spinothalamic, Spinomesencephalic, spinoreticular, spino-emotional
spinothalamic
conscious relay
discriminative nociception and temp
Spinomesencephalic, spinoreticular, and spino-emotional
divergent
slow nociception
nociceptive pain
associated with tissue damage or potential tissue damage
non-nociceptive pain
experienced independently of tissue damage
-dysfunction of neural pain regulating mechanisms
-neuropathic pain or central sensitivity syndromes
pain from muscles and joints is carried on what fibers
A delta and C fibers
peripheral sensitization
excessive reactivity to stimulus
referred pain
pain perceived as coming from a site distinct from the actual site of the origin
gate theory
info from first order mechanical afferents and nociceptive afferents converge on same second order neurons
-whichever is more active is what gets through the “gate” in the dorsal horn
counterirritant theory
nociceptive signals are inhibited by stimulation of non-nociceptive receptors in dorsal horn
allodynia
feel pain in repsonse to non-noxious stimuli
antinociception
suppression of the nociception in response to stimulus that would normally be painful
5 levels of antinociception
periphery, dorsal horn, fast acting descending system, hormonal, and amygdala and cortex
pronociception
intensification of nociceptive transmission
-edema makes pain worse
what does hyperactivity of the HPA system do to pain
it intensifies the pain
neuropathic pain
lesion or disease that is affecting the nerve
paresthesia
painless abnormal sensation
dyesthesia
unpleasant abnormal sensation
ectopic foci
abnormal location generates action potentials
ephaptic
transmissions coming from different places and signals synapse/connect with each other
central sensitization
excessive responsiveness of central neurons
deafferrentation
disruption of afferent signals anywhere along somatosensory along somatosensory pathway
complex regional pain syndrome
aberrant response to trauma
- severe, spontaneous pain out of proportion to original injury