PAHs

Question 1

Name the two types of PAHs

Answer 1

Pyrogenic and Petrogenic

Question 2

This type of PAH is formed from incomplete combustion @ high temp’s

Answer 2

pyrogenic

Question 3

This type of PAH is formed @ relatively low temp’s over geologic time scales; likely to be alkylated

Answer 3

petrogenic

Question 4

PAHs always occur as _____

Answer 4

mixtures

Question 5

What is Narcosis?

Answer 5

Dramatic slowing of all resp & cardiovascular activity

Question 6

What does FATS stand for?

Answer 6

Fish Aquatic Toxicity Syndrome

Question 7

Does narcosis produce a chemical or physical change?

Answer 7

Physical

Question 8

Narcosis is correlated with _______

Answer 8

lipophilicity

Question 9

PAHs are type ___ narcotic chemicals

Answer 9

Type I

Question 10

What is the Ferguson principle?

Answer 10

equal potency results when an equil exists b/w the biophase (biological organism/cellular membranes) and the environment and the agents have equal conc’s @ the site of action rather than when the agents have equal envir concentrations;

Question 11

According to the Ferguson principle, what is the rate-limiting step of narcosis?

Answer 11

The ability of the agent to reach the site of action

Question 12

What does QSAR stand for and what is its significance?

Answer 12

Quantitative Structure Activity Relationships - if we know the toxicity of a chem w/ a given stxr, we should be able to predict the toxicity of chem’s w/ a similar or related structure